Evidence map›Paper›PMID 36139450›Full record

ArticleCells2022

High-Dose

Kristina Ritter, Jochen Behrends, Dominik Rückerl, Alexandra Hölscher, Johanna Volz, Immo Prinz, Christoph Hölscher

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kristina RitterInfection Immunology, Research Center Borstel, D-23845 Borstel, Germany.
Jochen BehrendsFluorescence Cytometry Core Unit, Research Center Borstel, D-23845 Borstel, Germany.ORCID 0000-0002-0648-8911
Dominik RückerlLydia Becker Institute of Immunology and Inflammation, School of Biological Sciences, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-0206-1451
Alexandra HölscherInfection Immunology, Research Center Borstel, D-23845 Borstel, Germany.
Johanna VolzInfection Immunology, Research Center Borstel, D-23845 Borstel, Germany.
Immo PrinzCenter for Molecular Neurobiology Hamburg, Eppendorf University Medical Center, D-20246 Hamburg, Germany.ORCID 0000-0002-8789-9578
Christoph HölscherInfection Immunology, Research Center Borstel, D-23845 Borstel, Germany.ORCID 0000-0002-7520-9146
Research Center Borstel - Leibniz Lung Center · DEGerman Center for Infection Research · DEUniversität Hamburg · DEUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During experimental tuberculosis (TB), interleukin (IL)-17A appears to be involved in the formation of lung granulomas, possibly through the attraction of neutrophils to the sites of infection. However, the protective impact of cytokine appears to depend on the degree of its induction. Hence, robust production of IL-17A in mice infected with the hypervirulent isolate

Indexed as

Interleukin-17TuberculosisAnimalsCytokinesMiceMice, Inbred C57BLMice, KnockoutMycobacterium tuberculosisCytokinesInterleukin-17cytokinesIL-17AIL-17Fneutrophilsrodenttuberculosis

Identifiers

PMID36139450
PMCPMC9496946
OpenAlexW4296397145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.