Evidence map›Paper›PMID 36139274›Full record

ArticleAnimals : an open access journal from MDPI2022

Effects of Dietary 1,8-Cineole Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestine Health of Broilers.

Yuting Di, Aizhi Cao, Yuxin Zhang, Juntao Li, Yongbo Sun, Shixia Geng, Yongchen Li, Liying Zhang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Microorganisms · 2026
    Article
  3. Article
  4. Frontiers in veterinary science · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Phytogenics in Ginger,Animals : an open access journal from MDPI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuting DiState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Aizhi CaoState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Yuxin ZhangState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Juntao LiState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Yongbo SunState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Shixia GengState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Yongchen LiState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Liying ZhangState Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China.
Ministry of Agriculture and Rural Affairs · CNChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to investigate the effects of 1,8-cineole on antioxidant capacity, immunity, and intestinal health of broilers. A total of 540 1-day-old Arbor Acres (AA) male broilers were randomly divided into five treatments with six replicates per treatment, and 18 broilers per replicate for 42 days. Dietary treatments were a corn−soybean meal basal diet supplemented with 0, and 10, 20, 30, and 40 mg/kg 1,8-cineole, respectively. Dietary supplementation with 20~30 mg/kg of 1,8-cineole increased the ADG from d 22 to 42 and d 1 to 42 (p < 0.05), and decreased the FCR (p < 0.05). Dietary supplementation of 10~40 mg/kg of 1,8-cineole increased total antioxidant capacity (TAOC) in serum (p < 0.05), and decreased malondialdehyde (MDA) level in the liver on day 21 (p < 0.05). The supplementation of 20~30 mg/kg of 1,8-cineole increased the activity of total superoxide dismutase (T-SOD) in the serum and liver and TAOC in the serum and the liver (p < 0.05), and decreased the level of MDA in the serum and the liver (p < 0.05) on day 42. Dietary supplementation with 20~30 mg/kg of 1,8-cineole increased serum immunoglobulin A, immunoglobulin G, and immunoglobulin M contents on day 21 (p < 0.05). On day 21, dietary supplementation of 20~30 mg/kg of 1,8-cineole increased the VH and VH/CD (p < 0.05) in the jejunum and ileum. The supplementation of 20~30 mg/kg of 1,8-cineole increased the content of secretory immunoglobulin A in the duodenum and ileum mucosa on d 42 (p < 0.05). In conclusion, dietary supplementation of 1,8-cineole improves the growth performance of broilers by enhancing antioxidant capacity, immunity, and intestinal morphology.

Indexed as

1,8-cineoleantioxidant capacitybroilergrowth performanceimmunityintestinal health

Identifiers

PMID36139274
PMCPMC9495220
OpenAlexW4295765972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.