Evidence map›Paper›PMID 36139210›Full record

ArticleAnimals : an open access journal from MDPI2022

Diversity of Mitochondrial DNA Haplogroups and Their Association with Bovine Antral Follicle Count.

Hongfei Liu, Junjun Zhai, Hui Wu, Jingyi Wang, Shaowei Zhang, Jie Li, Zhihan Niu, Chenglong Shen, Kaijuan Zhang, Zhengqing Liu and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Hongfei LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Junjun ZhaiCollege of Life Science, Yulin University, Yulin 719000, China.
Hui WuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Jingyi WangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Shaowei ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Jie LiCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Zhihan NiuCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Chenglong ShenCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Kaijuan ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Zhengqing LiuCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Fugui JiangShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250000, China.
Enliang SongShandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250000, China.ORCID 0000-0003-3107-1912
Xiuzhu SunCollege of Grassland Agriculture, Northwest A&F University, Yangling 712100, China.
Yongsheng WangCollege of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Xianyong LanCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Northwest A&F University · CNShandong Academy of Agricultural Sciences · CNYulin University · CN

Funding

Agricultural Improved Seed Project of Shandong Province 2020LZGC014
6 · The paper itself

Abstract

Maternal origins based on the bovine mitochondrial D-loop region are proven to have two main origins: Bos taurus and Bos indicus. To examine the association between the maternal origins of bovine and reproductive traits, the complete mitochondrial D-loop region sequences from 501 Chinese Holstein cows and 94 individuals of other breeds were analyzed. Based on the results obtained from the haplotype analysis, 260 SNPs (single nucleotide polymorphism), 32 indels (insertion/deletion), and 219 haplotypes were identified. Moreover, the nucleotide diversity (π) and haplotype diversity (Hd) were 0.024 ± 0.001 and 0.9794 ± 0.003, respectively, indicating the abundance of genetic resources in Chinese Holstein cows. The results of the median-joining network analysis showed two haplogroups (HG, including HG1 and HG2) that diverged in genetic distance. Furthermore, the two haplogroups were significantly (p < 0.05) correlated with the antral follicle (diameter ≥ 8 mm) count, and HG1 individuals had more antral follicles than HG2 individuals, suggesting that these different genetic variants between HG1 and HG2 correlate with reproductive traits. The construction of a neighbor-joining phylogenetic tree and principal component analysis also revealed two main clades (HG1 and HG2) with different maternal origins: Bos indicus and Bos taurus, respectively. Therefore, HG1 originating from the maternal ancestors of Bos indicus may have a greater reproductive performance, and potential genetic variants discovered may promote the breeding process in the cattle industry.

Indexed as

antral folliclesbovinematernal originmitochondrial DNA haplogroupovary

Identifiers

PMID36139210
PMCPMC9495067
OpenAlexW4295094533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.