Evidence map›Paper›PMID 36139106›Full record

ArticleBiomolecules2022

Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells.

Veronique Mathieu, Breana Laguera, Marco Masi, Sara Adriana Dulanto, Tanner W Bingham, Lucas W Hernandez, David Sarlah, Antonio Evidente, Denis L J Lafontaine, Alexander Kornienko and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Alkaloids Reported in the GenusInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Aqueous Extract of Leaves and Flowers ofBiochemistry research international · 2024
    Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Veronique MathieuDepartment of Pharmacotherapy and Pharmaceutics, Université libre de Bruxelles (ULB), 1050 Brussels, Belgium.
Breana LagueraDepartment of Chemistry and Biochemistry, Texas State University, San Marcos, TX 78666, USA.ORCID 0000-0002-8215-4032
Marco MasiDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0003-0609-8902
Sara Adriana DulantoDepartment of Pharmacotherapy and Pharmaceutics, Université libre de Bruxelles (ULB), 1050 Brussels, Belgium.
Tanner W BinghamRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, IL 61801, USA.
Lucas W HernandezRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, IL 61801, USA.
David SarlahRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0002-8736-8953
Antonio EvidenteDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-9110-1656
Denis L J LafontaineRNA Molecular Biology, Fonds de la Recherche Scientifique (F.R.S/FNRS), Université libre de Bruxelles (ULB), Biopark Campus, 6040 Gosselies, Belgium.ORCID 0000-0001-7295-6288
Alexander KornienkoDepartment of Chemistry and Biochemistry, Texas State University, San Marcos, TX 78666, USA.ORCID 0000-0003-2041-7367
Michelle A LaneNutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX 78666, USA.
Texas State University · USUniversité Libre de Bruxelles · BEUniversity of Illinois Urbana-Champaign · USUniversity of Naples Federico II · IT

Funding

South Texas Doctoral Bridge ProgramR25GM102783 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI OYAJOBI, BABATUNDE OLUKAYODE, WHITTEN, STEVEN T · 2013 to 2022
$3.1M
Acid-Sensitive Glioblastoma Prodrugs Derived from Ophiobolin AR15CA227680 · NCI · TEXAS STATE UNIVERSITY · PI KORNIENKO, ALEXANDER · 2019 to 2019
$462k
NCI NIH HHS R15 CA227680NIGMS NIH HHS R25 GM102783NIH HHS 1R15CA227680-01A1
6 · The paper itself

Abstract

Alkaloids isolated from members of the

Indexed as

AlkaloidsAmaryllidaceae AlkaloidsColonic NeoplasmsCell LineCell ProliferationCytokinesHumansMatrix Metalloproteinase 1PhenanthridinesVascular Endothelial Growth Factor AAlkaloidsAmaryllidaceae AlkaloidsCytokineshemanthaminelycorineMatrix Metalloproteinase 1narciclasinePhenanthridinesVascular Endothelial Growth Factor AAmaryllidaceaecolorectal cancerhaemanthamineinvasionlycorinemetastasisMMPnarciclasinepancratistatinpentraxin 3VEGF

Identifiers

PMID36139106
PMCPMC9496155
OpenAlexW4295211044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.