Evidence map›Paper›PMID 36139009›Full record

ArticleBiomolecules2022

Use of Bacterial Extracellular Vesicles for Gene Delivery to Host Cells.

Su-Im Kim, Jae Yeong Ha, Song-Yi Choi, Su-Hyung Hong, Heon-Jin Lee

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Su-Im KimDepartment of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Jae Yeong HaDepartment of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Song-Yi ChoiDepartment of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Su-Hyung HongDepartment of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.ORCID 0000-0001-5569-3826
Heon-Jin LeeDepartment of Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.ORCID 0000-0002-1911-5014
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs), which are nanosized membranous particles secreted from both prokaryotic and eukaryotic cells, can deliver various biological molecules, such as nucleic acids, proteins, and lipids, into recipient cells. However, contrary to what is known about eukaryotic EVs, whether bacterial EVs (bEVs) can be used as transporters for bioactive molecules is becoming a hot area of research. In this study, we electroporated enhanced green fluorescent protein (EGFP) genes and precursor microRNA of Cel-miR-39 (pre-Cel-miR-39) from isolated bEVs of

Indexed as

Extracellular VesiclesMicroRNAsAnimalsGene Transfer TechniquesLipidsMiceRNA-Induced Silencing ComplexLipidsMicroRNAsRNA-Induced Silencing Complexextracellular vesiclegene deliverymicroRNAvaccine

Identifiers

PMID36139009
PMCPMC9496234
OpenAlexW4293008880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.