Evidence map›Paper›PMID 36139007›Full record

ArticleBiomolecules2022

Galectins Differentially Regulate the Surface Glycosylation of Human Monocytes.

Dina B AbuSamra, Rafael Martínez-Carrasco, Pablo Argüeso

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dina B AbuSamraTufts Medical Center, Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA.ORCID 0000-0002-0974-5362
Rafael Martínez-CarrascoTufts Medical Center, Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA.ORCID 0000-0001-6718-5503
Pablo ArgüesoTufts Medical Center, Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA.ORCID 0000-0001-7321-9503
Tufts University · US

Funding

VISION RESEARCHP30EY003790 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore · 1985 to 2026
$25.5M
N-Glycosylation and Ocular Surface HomeostasisR01EY026147 · NEI · TUFTS MEDICAL CENTER · PI Pablo Argueso · 2016 to 2026
$5.1M
Regulation of the immune cell glycome in corneal injuryR01EY030928 · NEI · TUFTS MEDICAL CENTER · PI ARGUESO, PABLO · 2020 to 2023
$1.1M
NEI NIH HHS P30 EY003790NEI NIH HHS P30EY003790NEI NIH HHS R01 EY026147NEI NIH HHS R01EY026147NEI NIH HHS R01 EY030928NEI NIH HHS R01EY030928
6 · The paper itself

Abstract

Monocytes are circulating blood cells that rapidly mobilize to inflamed sites where they serve diverse effector functions shaped in part by microenvironmental cues. The establishment of specific glycosylation patterns on the immune cell glycocalyx is fundamental to direct the inflammatory response, but relatively little is known about the mechanisms whereby the microenvironment controls this process. Here, we report that galectins differentially participate in remodeling the surface glycosylation of human primary CD14

Indexed as

Galectin 1MonocytesEpitopesGalactoseGalectin 3GalectinsGlycosylationHumansMucinsEpitopesGalactoseGalectin 1Galectin 3GalectinsMucinsgalectinsinflammationlectinmonocytesurface glycosylation

Identifiers

PMID36139007
PMCPMC9496102
OpenAlexW4293029260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.