ReviewBrain sciences2022
What Do We Know about Social and Non-Social Factors Influencing the Pathway from Cognitive Health to Dementia? A Systematic Review of Reviews.
Review in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Evaluating the association of physical frailty with cognitive impairment: a clinical perspective in older adults of Bangladesh.BMC geriatrics · 2026Article
- Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset.Frontiers in public health · 2026Article
- Longitudinal Engagement in Modifiable Lifestyle Behaviors and Racial-Ethnic Differences in Dementia Risk.Journal of aging and health · 2025Article
- Recent advancements in the understanding of the alterations in mitochondrial biogenesis in Alzheimer's disease.Molecular biology reports · 2025Review
- Effectiveness of Robot Care Intervention and Maintenance for People with Dementia: A Systematic Review and Meta-Analysis.Innovation in aging · 2025Review
- Social interaction of people living with dementia in residential long-term care: an ecological momentary assessment study.BMC health services research · 2024Article
- The association between malnutrition, depression and cognitive decline in free-living elderly people in Cyprus: a cross-sectional study.BMC public health · 2024Article
- Social connections as determinants of cognitive health and as targets for social interventions in persons with or at risk of Alzheimer's disease and related disorders: a scoping review.International psychogeriatrics · 2024Article
- Social activities in multidomain dementia prevention interventions: insights from practice and a blueprint for the future.Frontiers in psychiatry · 2024Article
- Fostering social health of people with dementia: evaluation ofFrontiers in public health · 2024Article
- Life-Course Multidisciplinary Psychosocial Predictors of Dementia Among Older Adults: Results From the Health and Retirement Study.Innovation in aging · 2024Article
- Instruments for assessing social health in the context of cognitive decline and dementia: a systematic review.Frontiers in psychiatry · 2024Review
- Article
- Association between cardiovascular diseases and dementia among various age groups: a population-based cohort study in older adults.Scientific reports · 2023Article
- Dietary Patterns and Alzheimer's Disease: An Updated Review Linking Nutrition to Neuroscience.Nutrients · 2023Review
- Beneficial and Impeding Factors for the Implementation of Health-Promoting Lifestyle Interventions-A Gender-Specific Focus Group Study.International journal of environmental research and public health · 2023Article
- Diabetes and cognitive function: An evidence-based current perspective.World journal of diabetes · 2023Review
- Influence of the Demographic, Social, and Environmental Factors on the COVID-19 Pandemic-Analysis of the Local Variations Using Geographically Weighted Regression.International journal of environmental research and public health · 2022Article
- Recognition of social health: A conceptual framework in the context of dementia research.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
The heterogeneous and multi-factorial nature of dementia requires the consideration of all health aspects when predicting the risk of its development and planning strategies for its prevention. This systematic review of reviews provides a comprehensive synthesis of those factors associated with cognition in the context of dementia, identifying the role of social aspects and evidencing knowledge gaps in this area of research. Systematic reviews and meta-analyses from 2009-2021 were searched for within Medline, PsycINFO, CINAHL Complete, Cochrane, and Epistemonikos. Reviewers independently screened, reviewed, and assessed the records, following the PRISMA-2020 guidelines. From 314 included studies, 624 cognitive-related factors were identified, most of them risk factors (61.2%), mainly belonging to the group of 'somatic comorbidities' (cardiovascular disease and diabetes) and 'genetic predispositions'. The protective factors (20%) were mainly related to lifestyle, pointing to the Mediterranean diet, regular physical activity, and cognitively stimulating activities. Social factors constituted 9.6% of all identified factors. Research on biological and medical factors dominates the reviewed literature. Greater social support and frequent contact may confer some protection against cognitive decline and dementia by delaying its onset or reducing the overall risk; however, overall, our findings are inconsistent. Further research is needed in the fields of lifestyle, psychology, social health, and the protective factors against cognitive decline and dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.