Evidence map›Paper›PMID 36138703›Full record

ArticleChildren (Basel, Switzerland)2022

Time of Onset and Risk Factors of Renal Involvement in Children with Henoch-Schönlein Purpura: Retrospective Study.

Nicolina Stefania Carucci, Giulia La Barbera, Licia Peruzzi, Antonella La Mazza, Lorena Silipigni, Angela Alibrandi, Domenico Santoro, Roberto Chimenz, Giovanni Conti

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nicolina Stefania CarucciPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.
Giulia La BarberaPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.
Licia PeruzziPediatric Nephrology Unit, Regina Margherita Department, Azienda Ospedaliero-Universitaria Città Della Salute E Della Scienza, 10126 Torino, Italy.ORCID 0000-0002-5704-3867
Antonella La MazzaPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.
Lorena SilipigniPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.
Angela AlibrandiUnit of Statistical and Mathematical Sciences, Department of Economics, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-6695-151X
Domenico SantoroUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Roberto ChimenzPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-9143-4637
Giovanni ContiPediatric Nephrology and Rheumatology Unit, AOU G Martino, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-0617-500X
University of Messina · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHenoch-Schönlein purpura (HSP) is a common systemic vasculitis in children, involving the skin, musculoskeletal system, gastrointestinal tract and kidneys. Some studies in children have shown possible risk factors linked with the development and severity of HSP Nephritis (HSPN). The aim of this study was to research predicting factors for the development of HSPN.

methodsWe retrospectively evaluated 132 pediatric patients with HSP, according to EULAR/PRINTO/PRESS criteria. All patients were screened for HSPN by urinalysis. Finally, we compared demographic, clinical and laboratory data in HSP patients with and without nephritis.

resultsThe median age at HSP diagnosis [6.2 (2.6-17.5) vs. 5.5 (0.8-15.4) years,

conclusionsThe age at diagnosis and abdominal pain were independent risk factors for renal involvement in HSP patients. However, due to the retrospective nature of this study, further long-term and prospective studies will be necessary.

Indexed as

abdominal painchildrenHenoch-Schönlein purpurakidneylaboratory datanephritisonsetrisk factors

Identifiers

PMID36138703
PMCPMC9497900
OpenAlexW4296103261

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.