Evidence map›Paper›PMID 36138699›Full record

ArticleChildren (Basel, Switzerland)2022

The Effectiveness of Different Eradication Schemes for Pediatric

Oana-Maria Rosu, Nicoleta Gimiga, Gabriela Stefanescu, Ileana Ioniuc, Elena Tataranu, Gheorghe G Balan, Laura-Mihaela Ion, Doina Anca Plesca, Cristina Gabriela Schiopu, Smaranda Diaconescu

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Antibiotics (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Prevalence of OralClinical and experimental gastroenterology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Oana-Maria RosuDoctoral School, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Str., 540139 Targu Mures, Romania.
Nicoleta GimigaFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.ORCID 0000-0002-8713-5367
Gabriela StefanescuFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.ORCID 0000-0003-2329-7970
Ileana IoniucFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.ORCID 0000-0003-3992-6751
Elena TataranuClinical Department of Pediatrics, "Sf. Ioan cel Nou" Emergency Hospital, 720224 Suceava, Romania.
Gheorghe G BalanFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
Laura-Mihaela IonFaculty of Medicine, "Titu Maiorescu" University of Medicine, 67A Gheorghe Petrascu Str., 031593 Bucharest, Romania.
Doina Anca PlescaFaculty of medicine, "Carol Davila" University of Medicine and Pharmacy, 21 Dionisie Lupu Str., 020021 Bucharest, Romania.ORCID 0000-0002-8849-6834
Cristina Gabriela SchiopuFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Str., 700115 Iasi, Romania.
Smaranda DiaconescuFaculty of Medicine, "Titu Maiorescu" University of Medicine, 67A Gheorghe Petrascu Str., 031593 Bucharest, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROTitu Maiorescu University · ROCarol Davila University of Medicine and Pharmacy · ROŞtefan cel Mare University of Suceava · ROUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Romania, studies on the pediatric population regarding

methodsThe prospective study enrolled children aged 6-17 years who were first diagnosed with

results149 patients were enrolled over 18 months. The eradication rates were 49.5% for the treatment scheme with proton pump inhibitor (PPI) + amoxicillin (AMO) + MTZ, 26.7% for PPI + AMO + CLR and 23.8% for sequential therapy. MTZ therapy was superior to CLR therapy, but sequential therapy was not. Side effects were recorded for PPI + AMO + CLR with 39.6%, followed by sequential therapy 37.7%, and only 22.6% for PPI + AMO + MTZ.

conclusionsTherapy with MTZ can achieve a higher eradication rate as a first-line treatment in the case of

Indexed as

childreneradicationHelicobacter pyloritreatment

Identifiers

PMID36138699
PMCPMC9497595
OpenAlexW4295766182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.