Evidence map›Paper›PMID 36138480›Full record

ArticleBiomedical engineering online2022

A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study.

Gabriela Albuquerque, Agnaldo Cruz, Dionísio Carvalho, Nadja Mayrink, Bruno Pinheiro, Antonio Campos, Josivan Gomes Lima, Jorge Henriques, Ricardo Valentim

Open access · goldAbstract read
In one paragraph

Article in Biomedical engineering online, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Gabriela AlbuquerqueAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil. gabriela.albuquerque@lais.huol.ufrn.br.
Agnaldo CruzAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Dionísio CarvalhoAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Nadja MayrinkAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Bruno PinheiroAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Antonio CamposAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Josivan Gomes LimaOnofre Lopes University Hospital, Natal, Brazil.
Jorge HenriquesDepartment of Informatics Engineering, University of Coimbra, Centre for Informatics and Systems of the University of Coimbra, Coimbra, Portugal.
Ricardo ValentimAdvanced Technological Innovation Nucleus-NAVI, Federal Institute of Rio Grande Do Norte, Natal, RN, Brazil.
Universidade Federal do Rio Grande do Norte · BRHospital Universitário Onofre Lopes · BRUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is a condition characterized by low bone mineral density, which typically leads to fractures and reduced quality of life. Currently, diagnostic devices used to assess this condition (e.g., dual-energy X-ray absorptiometry) are very costly, making it infeasible to meet the demand for testing in most countries. Therefore, we proposed a preclinical validation of a prototype called Osseus in an attempt to enhance osteoporosis screening tests and alleviate their costs. Osseus is a device developed to assist bone mineral density classification. It integrates a microcontroller into other peripheral devices to measure the attenuation at the middle phalanx of the middle finger, with two antennas operating at the 2.45 GHz frequency.

resultsWe conducted tests with plaster, poultry, and porcine bones. A comparison of the measurements of the original and mechanically altered samples demonstrated that the device can handle the complexity of the tissues within the bone structure and characterize its microarchitecture.

conclusionsOsseus is a device that has been preliminarily validated. Ionising radiation needed for DXA tests is replaced by non-ionising microwave electromagnetic radiation. Osseus enables early detection of osteoporosis, reduces costs, and optimizes high-complexity testing referrals. There is a lack of validation studies with the reference/gold standard that are currently under development.

Indexed as

MicrowavesOsteoporosisAbsorptiometry, PhotonBone DensityHumansMineralsPilot ProjectsQuality of LifeMineralsOsseusBone mineral densityMedical deviceMicrowaveOsseusOsteoporosis

Identifiers

PMID36138480
PMCPMC9494783
OpenAlexW4296810518

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.