Evidence map›Paper›PMID 36138418›Full record

ArticleBMC research notes2022

CD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice.

Diego Maximo Aguilera-Braico, Gabriela A Balogh

Abstract read
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Diego Maximo Aguilera-BraicoBIOMED-UCA, Laboratory of Biomedical Sciences, Pontifical Catholic Argentine University-UCA, 1600 Alicia Moreau de Justo Avenue, 1007, Buenos Aires, Argentina.
Gabriela A Balogh, 64 Jewel Lane, Levittown, Pennsylvania, 19055, USA. gabriela_balogh@uca.edu.ar.ORCID http://orcid.org/0000-0001-8836-3284

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas Beca Doctoral
6 · The paper itself

Abstract

objectivesThe aim of this research was to determine if the rich beta glucan compound called Maitake Pro4X can recover the T cell/NK population depleted by Dexamethasone treatment in lymph nodes from cancer-free BALBc female mice. A CD3Ɛ molecular FITC labelled marker was used to measure the effect of Maitake D-Fraction Pro4X (5 mg/kg) on T cell/NK cells populations employing flow cytometry from immunosuppressed female BALBc mice in lymph nodes. There were employed other molecular markers such as CD19, CD105, Ly6G.

resultsMaitake Pro4X (5 mg/kg) was able to recover 42.97% of the depleted CD3Ɛ FITC cell population level in Lymph nodes from immunosuppressed female BALBc mice from 4.328 ± 6.229 to 22.646 ± 12.393 (p < 0.01) using Flow Cytometry. Maitake was also able to significantly increase the Ly6G PE cell population with p < 0.05 in lymph nodes.

Indexed as

beta-GlucansGrifolaAdjuvants, ImmunologicAnimalsDexamethasoneFemaleFluorescein-5-isothiocyanateMiceAdjuvants, Immunologicbeta-GlucansDexamethasoneFluorescein-5-isothiocyanateBL/stem cellsGranulocytesImmunosuppressionMaitake D-Fraction Pro4XTL /NK cells

Identifiers

PMID36138418
PMCPMC9502923

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.