Evidence map›Paper›PMID 36138286›Full record

ArticleAnnals of surgical oncology2022

Racial Disparities in Surgical Outcomes Among Women with Endometrial Cancer.

Ashley S Felix, Toluwaniose Nafiu, Casey M Cosgrove, Aldenise P Ewing, Christian Mpody

Open access · greenAbstract read
In one paragraph

Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Racioethnic Disparities in Endometrial Cancer Outcomes.Diagnostics (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Racial Disparities in Outcomes of Bariatric Surgery: An Analysis of 190,319 Patients.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashley S FelixDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA. ashley.felix@osumc.edu.
Toluwaniose NafiuDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA.
Casey M CosgroveDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, The Ohio State University, Columbus, OH, USA.
Aldenise P EwingDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA.
Christian MpodyDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
The Ohio State University · USNationwide Children's Hospital · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Effect of adiposity changes on endometrial tissue and blood biomarkers in women at increased risk for endometrial cancerK01CA218457 · NCI · OHIO STATE UNIVERSITY · PI FELIX, ASHLEY S. · 2018 to 2022
$703k
NCI NIH HHS K01 CA218457NCI NIH HHS K01CA218457-01A1NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

purposeEndometrial cancer (EC) is the most common gynecological cancer among women in the United States. Despite well-documented racial/ethnic disparities in EC incidence and mortality rates, limited data exist regarding disparities in hysterectomy surgical outcomes. We evaluated associations of race/ethnicity with postoperative complications, serious adverse events (SAEs), and length of hospital stay among women undergoing EC-related hysterectomy.

methodsUsing National Surgical Quality Improvement Program (NSQIP) data, we identified women (≥18 years) undergoing hysterectomy to treat EC between 2014 and 2020. We used multivariable logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations of race/ethnicity (white, black, and Latina) with postoperative complications and SAEs. We used Poisson regression with robust standard errors to calculate incidence rate ratios (IRRs) and 95% CIs for the association of race/ethnicity with length of hospital stay.

resultsOf 22,778 women undergoing EC-related hysterectomy, 3.1% developed postoperative complications. Black (adjusted OR: 1.62; 95% CI 1.05-2.48) and Latina women (adjusted OR: 1.79; 95% CI 1.04-3.09) had higher postoperative complication risks than white women. The overall SAE incidence was 5.0%. Black women (adjusted OR: 1.55, 95% CI 1.13-2.15) had higher SAE risks than white women. Length of hospital stay was significantly longer for black women than white women (IRR: 1.18; 95% CI 1.07-1.30).

conclusionsWe observed racial/ethnic disparities in EC-related hysterectomy surgical outcomes in a large, diverse sample of U.S. women between 2014 and 2020. Studies to elucidate the underlying mechanisms of these racial disparities, with a focus on social context remain necessary.

Indexed as

Black or African AmericanEndometrial NeoplasmsFemaleHealthcare DisparitiesHumansPostoperative ComplicationsTreatment OutcomeUnited States

Identifiers

PMID36138286
PMCPMC10316673
OpenAlexW4296802086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.