Evidence map›Paper›PMID 36138184›Full record

ArticleNature immunology2022

tRNA-m

Yongbo Liu, Jing Zhou, Xiaoyu Li, Xiaoting Zhang, Jintong Shi, Xuefei Wang, Hao Li, Shan Miao, Huifang Chen, Xiaoxiao He and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 112 citations in OpenAlex.

  1. Blocking the mCellular & molecular immunology · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. RNA Helicase DDX21 Controls CD4Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Blocking the mNature communications · 2026
    Article
  8. tRNA mEMBO reports · 2026
    Article
  9. mPharmaceuticals (Basel, Switzerland) · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. tRNA modifications in viral replication.The Journal of biological chemistry · 2026
    Review
  14. mScience advances · 2026
    Article
  15. Review
  16. Review
  17. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  18. Regulation of RNA-binding proteins by small biomolecules.Nature reviews. Molecular cell biology · 2026
    Review
  19. tRNA mCellular & molecular immunology · 2026
    Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 3 countries.

Yongbo Liu *Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing Zhou *Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-6601-4446
Xiaoyu Li *Department of Biochemistry and Department of Gastroenterology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaoting Zhang *State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Jintong Shi *Shanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xuefei WangShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hao LiSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Shan MiaoShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huifang ChenShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoxiao HeHongqiao International Institute of Medicine, Shanghai Tongren Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liting DongState Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Gap Ryol LeeDepartment of Life Science, Sogang University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-6412-9482
Junke ZhengHongqiao International Institute of Medicine, Shanghai Tongren Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ru-Juan LiuSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Bing SuShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-0871-7666
Youqiong YeShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-8332-4710
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. richard.flavell@yale.edu.ORCID http://orcid.org/0000-0003-4461-0778
Chengqi YiState Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China. chengqi.yi@pku.edu.cn.ORCID http://orcid.org/0000-0003-2540-9729
Yuzhang WuChongqing International Institute for Immunology, Chongqing, China. wuyuzhang@iiicq.vip.ORCID http://orcid.org/0000-0002-4049-0214
Hua-Bing LiShanghai Institute of Immunology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China. huabing.li@shsmu.edu.cn.ORCID http://orcid.org/0000-0003-3573-6803
Shanghai Jiao Tong University · CNPeking University · CNHoward Hughes Medical Institute · USSecond Affiliated Hospital of Zhejiang University · CNShanghaiTech University · CNSichuan International Studies University · CNSogang University · KR

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Naive T cells undergo radical changes during the transition from dormant to hyperactive states upon activation, which necessitates de novo protein production via transcription and translation. However, the mechanism whereby T cells globally promote translation remains largely unknown. Here, we show that on exit from quiescence, T cells upregulate transfer RNA (tRNA) m

Indexed as

ColitisRNA, TransferAdoptive TransferAnimalsCell ProliferationMiceProtein BiosynthesisT-LymphocytesRNA, Transfer

Identifiers

PMID36138184
OpenAlexW4296795237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.