Evidence map›Paper›PMID 36138135›Full record

ReviewNature cancer2022

Artificial intelligence in histopathology: enhancing cancer research and clinical oncology.

Artem Shmatko, Narmin Ghaffari Laleh, Moritz Gerstung, Jakob Nikolas Kather

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 236 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
236citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

236 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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176 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Artem Shmatko *Division of AI in Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-2184-0856
Narmin Ghaffari Laleh *Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Moritz GerstungDivision of AI in Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. moritz.gerstung@dkfz.de.ORCID http://orcid.org/0000-0001-6709-963X
Jakob Nikolas KatherDepartment of Medicine III, University Hospital RWTH Aachen, Aachen, Germany. jakob_nikolas.kather@tu-dresden.de.ORCID http://orcid.org/0000-0002-3730-5348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative information from digital histopathology images. AI is expected to reduce workload for human experts, improve the objectivity and consistency of pathology reports, and have a clinical impact by extracting hidden information from routinely available data. Here, we describe how AI can be used to predict cancer outcome, treatment response, genetic alterations and gene expression from digitized histopathology slides. We summarize the underlying technologies and emerging approaches, noting limitations, including the need for data sharing and standards. Finally, we discuss the broader implications of AI in cancer research and oncology.

Indexed as

Artificial IntelligenceNeoplasmsHumansMedical OncologyResearch

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.