Evidence map›Paper›PMID 36138068›Full record

ArticleBone marrow transplantation2022

Comparative study of treosulfan plus Fludarabine (FT14) with busulfan plus Fludarabine (FB4) for acute myeloid leukemia in first or second complete remission: An analysis from the European Society for Blood and Marrow Transplantation (EBMT) Acute Leukemia Working Party (ALWP).

Eleni Gavriilaki, Myriam Labopin, Ioanna Sakellari, Urpu Salmenniemi, Ibrahim Yakoub-Agha, Victoria Potter, Ana Berceanu, Alessandro Rambaldi, Inken Hilgendorf, Nicolaus Kröger and 12 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Eleni GavriilakiHematology Department-BMT Unit, G Papanikolaou Hospital, Thessaloniki, Greece. elenicelli@yahoo.gr.ORCID 0000-0002-8883-8208
Myriam LabopinService d' Hématologie Clinique et Thérapie Cellulaire, Hospital Saint-Antoine, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), Paris, France.ORCID 0000-0003-4514-4748
Ioanna SakellariHematology Department-BMT Unit, G Papanikolaou Hospital, Thessaloniki, Greece.
Urpu SalmenniemiHUCH Comprehensive Cancer Center, Stem Cell Transplantation Unit - Helsinki, Helsinki, Finland.
Ibrahim Yakoub-AghaCHU de Lille, univ Lille, INSERM U1286, Infinite, 59000, Lille, France.ORCID 0000-0003-4524-8782
Victoria PotterKings College Hospital, Dept. of Haematological Medicine, King's Denmark Hill Campus - London, London, UK.
Ana BerceanuHopital Jean Minjoz, Service d'Hématologie - Besançon, Besançon, France.
Alessandro RambaldiDepartment of Oncology and Hematology, University of Milan and Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Inken HilgendorfUniversitaetsklinikum Jena, Klinik für Innere Medizin II - Jena, Jena, Germany.ORCID 0000-0003-2038-9730
Nicolaus KrögerUniversity Hospital Eppendorf, Bone Marrow Transplantation Centre - Hamburg, Hamburg, Germany.ORCID 0000-0001-5103-9966
Stephan MielkeKarolinska University Hospital, Dept. of Hematology - Stockholm, Stockholm, Sweden.
Tsila ZuckermanRambam Medical Center, Dept. of Hematology & BMT - Haifa, Haifa, Israel.ORCID 0000-0002-6204-977X
Jaime SanzUniversity Hospital La Fe, Hematology Department - Valencia, Valencia, Spain.ORCID 0000-0001-6934-4619
Alessandro BuscaS.S.C.V.D Trapianto di Cellule Staminali, A.O.U Citta della Salute e della Scienza di Torino, Torino, Italy.ORCID 0000-0001-5361-5613
Hakan OzdoguBaskent University Hospital, Haematology Division, BMT Unit, Haematology Reserach Laboratory, Training & Medical - Adana, Adana, Turkey.ORCID 0000-0002-8902-1283
Achilles AnagnostopoulosHematology Department-BMT Unit, G Papanikolaou Hospital, Thessaloniki, Greece.ORCID 0000-0003-4384-9031
Bipin SavaniVanderbilt University Medical Center, Division of Hematology/ Oncology, Nashville, TN, USA.ORCID 0000-0002-3304-9965
Sebastian GiebelMaria Sklodowska-Curie Institute, Department of Bone Marrow Transplantation and Oncohematology, Oncology Center - Gliwice, Gliwice, Poland.ORCID 0000-0002-4827-4401
Ali BazarbachiAmerican University of Beirut, Medical Center, Department of Internal Medicine - Beirut, Beirut, Lebanon.ORCID 0000-0002-7171-4997
Alexandros SpyridonidisDepartment of Internal Medicine, Bone Marrow Transplantation Unit, University Hospital of Patras, Patras, Greece.ORCID 0000-0003-3097-2532
Arnon NaglerChaim Sheba Medical Center, Dept. of Bone Marrow Transplantation - Tel-Hashomer, Tel-Hashomer, Israel.ORCID 0000-0002-0763-1265
Mohamad MohtyService d' Hématologie Clinique et Thérapie Cellulaire, Hospital Saint-Antoine, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), Paris, France.ORCID 0000-0002-7264-808X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different doses of treosulfan plus fludarabine have shown advantage over reduced intensity regimens. However, data comparing higher doses of treosulfan to myeloablative busulfan are limited. Thus, we compared outcomes between FT14 (fludarabine 150/160 mg/m

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAcute DiseaseAdultBone MarrowBusulfanFemaleHumansMaleRetrospective StudiesTransplantation ConditioningVidarabineBusulfanfludarabinetreosulfanVidarabine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.