ArticleUltrasound in medicine & biology2022
Beyond Simpson's Rule: Accounting for Orientation and Ellipticity Assumptions.
Article in Ultrasound in medicine & biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- AI-enabled left atrial volume quantification from CAC CT: comparison with echocardiography.The international journal of cardiovascular imaging · 2026Article
- Electroacupuncture and conventional drugs treatment combination improved quality of life in patients with heart failure reduced ejection fraction: a single-blinded randomized controlled trial.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Is This a "True" Apical Sparing Pattern?CASE (Philadelphia, Pa.) · 2025Article
- Automated ejection fraction and risk stratification in cardiomyopathy patients with diverse LV geometry using 2D echocardiography.Scientific reports · 2025Article
- Speckle-Tracking Echocardiography in Dogs: Evaluating Imaging Parameters and Methodological Variability in Global Longitudinal Strain Assessment.Animals : an open access journal from MDPI · 2025Article
- Assessment of left ventricular systolic function using a non-invasive index of myocardial work in amateur marathon runners.Quantitative imaging in medicine and surgery · 2024Article
- Left ventricular ejection fraction: clinical, pathophysiological, and technical limitations.Frontiers in cardiovascular medicine · 2024Review
- Cardiovascular magnetic resonance versus echocardiography derived left ventricular ejection fraction for decision-making.Future cardiologyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Simpson's biplane rule (SBR) is considered the gold standard method for left ventricle (LV) volume quantification from echocardiography but relies on a summation-of-disks approach that makes assumptions about LV orientation and cross-sectional shape. We aim to identify key limiting factors in SBR and to develop a new robust standard for volume quantification. Three methods for computing LV volume were studied: (i) SBR, (ii) addition of a truncated basal cone (TBC) to SBR and (iii) a novel method of basal-oriented disks (BODs). Three retrospective cohorts representative of the young, adult healthy and heart failure populations were used to study the impact of anatomical variations in volume computations. Results reveal how basal slanting can cause over- and underestimation of volume, with errors by SBR and TBC >10 mL for slanting angles >6°. Only the BOD method correctly accounted for basal slanting, reducing relative volume errors by SBR from -2.23 ± 2.21% to -0.70 ± 1.91% in the adult population and similar qualitative performance in the other two cohorts. In conclusion, the summation of basal oriented disks, a novel interpretation of SBR, is a more accurate and precise method for estimating LV volume.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.