Evidence map›Paper›PMID 36137759›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Deep Learning-Based Attenuation Correction Improves Diagnostic Accuracy of Cardiac SPECT.

Aakash D Shanbhag, Robert J H Miller, Konrad Pieszko, Mark Lemley, Paul Kavanagh, Attila Feher, Edward J Miller, Albert J Sinusas, Philipp A Kaufmann, Donghee Han and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
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  5. Review
  6. Attenuation correction of cardiacEJNMMI physics · 2026
    Article
  7. Article
  8. Review
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  10. Article
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  12. Review
  13. Article
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  16. Radiation Detectors and Sensors in Medical Imaging.Sensors (Basel, Switzerland) · 2024
    Review
  17. Article
  18. Review
  19. Article
  20. The past, present, and future of attenuation correction for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Aakash D ShanbhagDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Robert J H MillerDepartment of Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada.
Konrad PieszkoDepartment of Interventional Cardiology and Cardiac Surgery, University of Zielona Góra, Zielona Góra, Poland.
Mark LemleyDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Paul KavanaghDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Attila FeherSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; and.
Edward J MillerSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; and.
Albert J SinusasSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; and.
Philipp A KaufmannCardiac Imaging, Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.
Donghee HanDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Cathleen HuangDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Joanna X LiangDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Daniel S BermanDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Damini DeyDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
Piotr J SlomkaDepartments of Medicine (Division of Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California; piotr.slomka@cshs.org.
Cedars-Sinai Medical Center · USYale University · USUniversity Hospital of Zurich · CHUniversity of Calgary · CAUniversity of Zielona Góra · PL

Funding

Quantitative Prediction of Disease and Outcomes from Next Generation SPECT and CTR01HL089765 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2007 to 2021
$6.1M
Patient-specific Outcome Prediction from Cardiovascular Multimodality Imaging by Artificial IntelligenceR35HL161195 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Piotr J Slomka · 2022 to 2026
$5.0M
NHLBI NIH HHS R01 HL089765NHLBI NIH HHS R35 HL161195
6 · The paper itself

Abstract

To improve diagnostic accuracy, myocardial perfusion imaging (MPI) SPECT studies can use CT-based attenuation correction (AC). However, CT-based AC is not available for most SPECT systems in clinical use, increases radiation exposure, and is impacted by misregistration. We developed and externally validated a deep-learning model to generate simulated AC images directly from non-AC (NC) SPECT, without the need for CT.

Indexed as

Coronary Artery DiseaseDeep LearningMyocardial Perfusion ImagingHumansROC CurveSensitivity and SpecificityTomography, Emission-Computed, Single-Photonartificial intelligenceattenuation correctiondeep learningmyocardial perfusion imagingSPECT

Identifiers

PMID36137759
PMCPMC10071806
OpenAlexW4296794342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.