Evidence map›Paper›PMID 36137264›Full record

ArticleJournal of the American Geriatrics Society2023

Excess deaths from COVID-19 among Medicare beneficiaries with psychiatric diagnoses: Community versus nursing home.

Huiwen Xu, Shuang Li, Hemalkumar B Mehta, Erin L Hommel, James S Goodwin

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Nursing home visitor policy and COVID-19 infection rates.American journal of infection control · 2025
    Article
  3. Article
  4. Lifting Federal Visitation Restriction and COVID-19 Infections in Nursing Homes.Journal of the American Medical Directors Association · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huiwen XuSchool of Public and Population Health, University of Texas Medical Branch, Galveston, Texas, USA.ORCID https://orcid.org/0000-0002-4033-0659
Shuang LiSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, USA.
Hemalkumar B MehtaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Erin L HommelSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, USA.ORCID https://orcid.org/0000-0003-1975-4008
James S GoodwinSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, USA.ORCID https://orcid.org/0000-0001-5507-1613
The University of Texas Medical Branch at Galveston · USJohns Hopkins University · US

Funding

UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
Drug-Drug Interactions Involving Direct-Acting Oral Anticoagulants in Nursing Home ResidentsK01AG070329 · NIA · JOHNS HOPKINS UNIVERSITY · PI MEHTA, HEMALKUMAR B. · 2021 to 2025
$647k
NCATS NIH HHS UL1 TR001439NIA NIH HHS K01 AG070329NIA NIH HHS P30 AG024832NIH HHS 1K01AG070329NIH HHS P30AG024832NIH HHS UL1-TR001439
6 · The paper itself

Abstract

backgroundPsychiatric illness may pose an additional risk of death for older adults during the COVID-19 pandemic. Older adults in the community versus institutions might be influenced by the pandemic differently. This study examines excess deaths during the COVID-19 pandemic among Medicare beneficiaries with and without psychiatric diagnoses (depression, anxiety, bipolar disorder, and schizophrenia) in the community versus nursing homes.

methodsThis is a retrospective cohort study of a 20% random sample of 15,229,713 fee-for-service Medicare beneficiaries, from January 2019 through December 2021. Unadjusted monthly mortality risks, COVID-19 infection rates, and case-fatality rates after COVID-19 diagnosis were calculated. Excess deaths in 2020, compared to 2019 were estimated from multivariable logistic regressions.

resultsOf all included Medicare beneficiaries in 2020 (N = 5,140,619), 28.9% had a psychiatric diagnosis; 1.7% lived in nursing homes. In 2020, there were 246,422 observed deaths, compared to 215,264 expected, representing a 14.5% increase over expected. Patients with psychiatric diagnoses had more excess deaths than those without psychiatric diagnoses (1,107 vs. 403 excess deaths per 100,000 beneficiaries, p < 0.01). The largest increases in mortality risks were observed among patients with schizophrenia (32.4% increase) and bipolar disorder (25.4% increase). The pandemic-associated increase in deaths with psychiatric diagnoses was only found in the community, not in nursing homes. The increased mortality for patients with psychiatric diagnoses was limited to those with medical comorbidities. The increase in mortality for psychiatric diagnoses was associated with higher COVID-19 infection rates (1-year infection rate = 7.9% vs. 4.2% in 2020), rather than excess case fatality.

conclusionsExcess deaths during the COVID-19 pandemic were disproportionally greater in beneficiaries with psychiatric diagnoses, at least in part due to higher infection rates. Policy interventions should focus on preventing COVID-19 infections and deaths among community-dwelling patients with major psychiatric disorders in addition to those living the nursing homes.

Indexed as

COVID-19Mental DisordersAgedCOVID-19 TestingHumansMedicareNursing HomesPandemicsRetrospective StudiesUnited StatesCOVID-19epidemiologyexcess deathsnursing homepsychiatric diagnoses

Identifiers

PMID36137264
PMCPMC9537955
OpenAlexW4296804069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.