Evidence map›Paper›PMID 36137252›Full record

ArticleJournal of the American Chemical Society2022

Ligand-Enabled C-H Hydroxylation with Aqueous H

Zhen Li, Han Seul Park, Jennifer X Qiao, Kap-Sun Yeung, Jin-Quan Yu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Alkyl-to-Alkyl Palladium Migration Enables Remote C-C Bond Formation.Journal of the American Chemical Society · 2026
    Article
  2. Diversity-Oriented C-H Activation Reactions of the Naphthalene Scaffold.Journal of the American Chemical Society · 2025
    Article
  3. From Mono-Accounts of chemical research · 2025
    Review
  4. Article
  5. Total Synthesis of the Nominal Structure of (+)-Talaromyolide D.Journal of the American Chemical Society · 2025
    Article
  6. Review
  7. Article
  8. Direct Pd-Catalyzed β-C(spOrganic letters · 2025
    Article
  9. Article
  10. Article
  11. Biopesticide Compounds from an Endolichenic FungusMolecules (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Review
  14. Direct C-H Hydroxylation ofJournal of the American Chemical Society · 2024
    Article
  15. Article
  16. Ligand-Enabled γ-C(spJournal of the American Chemical Society · 2023
    Article
  17. Ligand-Enabled Double γ-C(spAngewandte Chemie (International ed. in English) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhen LiThe Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0002-0815-9839
Han Seul ParkThe Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
Jennifer X QiaoSmall Molecule Drug Discovery, Bristol Myers Squibb Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
Kap-Sun YeungSmall Molecule Drug Discovery, Bristol Myers Squibb Research and Early Development, 100 Binney Street, Cambridge, Massachusetts 02142, United States.ORCID 0000-0003-3995-6555
Jin-Quan YuThe Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0003-3560-5774

Funding

Catalyst-Controlled Site-Selective C-H Functionalizations of Arenes and HeteroarenesR01GM102265 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2012 to 2023
$4.6M
NIGMS NIH HHS R01 GM102265
6 · The paper itself

Abstract

With the large number of Pd(II)-catalyzed C-H activation reactions of native substrates developed in the past decade, the development of catalysts to enable the use of green oxidants under safe and practical conditions has become an increasingly important challenge. Notably, the compatibility of Pd(II) catalysts with sustainable aqueous H

Indexed as

Biological ProductsHydrogen PeroxideCatalysisHydroxylationIbuprofenLigandsOxidantsPalladiumPhenolsPhenylacetatesPyridonesTemperatureWaterBiological ProductsHydrogen PeroxideIbuprofenLigandsOxidantsPalladiumPhenolsPhenylacetatesPyridonesWater

Identifiers

PMID36137252
PMCPMC10292862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.