Evidence map›Paper›PMID 36137053›Full record

ArticleScience (New York, N.Y.)2022

NIN-like protein 7 transcription factor is a plant nitrate sensor.

Kun-Hsiang Liu, Menghong Liu, Ziwei Lin, Zi-Fu Wang, Binqing Chen, Cong Liu, Aping Guo, Mineko Konishi, Shuichi Yanagisawa, Gerhard Wagner and 1 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
50.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 254 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification and characterization ofHorticulture research · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sentinel plants enable quantitative monitoring of bioavailable nitrate in soils and microbial environments.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Article
  13. Structure-informed engineering of plant-microbe interactions.The Plant journal : for cell and molecular biology · 2026
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  19. Article
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Kun-Hsiang Liu *State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.ORCID 0000-0003-1141-5554
Menghong Liu *State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.ORCID 0000-0002-7758-9525
Ziwei Lin *State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.
Zi-Fu Wang *Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Binqing Chen *State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.ORCID 0000-0001-5233-5097
Cong LiuState Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.ORCID 0000-0001-9172-6226
Aping GuoState Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.ORCID 0000-0003-3945-9604
Mineko KonishiAgro-Biotechnology Research Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0002-4503-2175
Shuichi YanagisawaAgro-Biotechnology Research Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0002-3758-5933
Gerhard WagnerDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-2063-4401
Jen SheenDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-8970-9267
Agriculture and Forestry University · NPHarvard University · USThe University of Tokyo · JP

Funding

Glucose Signal Transduction Pathways in PlantsR01GM060493 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2000 to 2017
$5.7M
Plant Nutrient-Growth Signaling NetworkR01GM129093 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2018 to 2025
$2.8M
NIGMS NIH HHS R01 GM060493NIGMS NIH HHS R01 GM129093
6 · The paper itself

Abstract

Nitrate is an essential nutrient and signaling molecule for plant growth. Plants sense intracellular nitrate to adjust their metabolic and growth responses. Here we identify the primary nitrate sensor in plants. We found that mutation of all seven

Indexed as

ArabidopsisArabidopsis ProteinsNitratesTranscription FactorsLigandsArabidopsis ProteinsLigandsNIN-LIKE PROTEIN7, ArabidopsisNitratesTranscription Factors

Identifiers

PMID36137053
PMCPMC9628810
OpenAlexW4296802323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.