ReviewPLoS genetics2022
Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution.
Review in PLoS genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Multicenter retrospective observational study on the clinical effectiveness of butyrate-producingVirulence · 2026Observational
- Uncovering heterogeneous intercommunity disease transmission from neutral allele frequency time series.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Repeated introductions and widespread transmission of human metapneumovirus in Côte d'Ivoire.BMC infectious diseases · 2025Article
- Catching a wave: On the suitability of traveling-wave solutions in epidemiological modeling.Theoretical population biology · 2025Article
- The Canadian VirusSeq Data Portal and Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology.Microbial genomics · 2024Article
- Article
- Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England.PLoS pathogens · 2024Article
- disperseNN2: a neural network for estimating dispersal distance from georeferenced polymorphism data.BMC bioinformatics · 2023Article
- disperseNN2: a neural network for estimating dispersal distance from georeferenced polymorphism data.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Theoretical population genetics has long studied the arrival and geographic spread of adaptive variants through the analysis of mathematical models of dispersal and natural selection. These models take on a renewed interest in the context of the COVID-19 pandemic, especially given the consequences that novel adaptive variants have had on the course of the pandemic as they have spread through global populations. Here, we review theoretical models for the spatial spread of adaptive variants and identify areas to be improved in future work, toward a better understanding of variants of concern in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) evolution and other contemporary applications. As we describe, characteristics of pandemics such as COVID-19-such as the impact of long-distance travel patterns and the overdispersion of lineages due to superspreading events-suggest new directions for improving upon existing population genetic models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.