Evidence map›Paper›PMID 36136973›Full record

ArticlePloS one2022

Continuous subcutaneous insulin infusion is associated with a better glycemic control than multiple daily insulin injections without difference in diabetic ketoacidosis and hypoglycemia admissions among Emiratis with Type 1 diabetes.

Raya Almazrouei, Charu Sharma, Bachar Afandi, Khaled M Aldahmani, Elhadi H Aburawi, Salem A Beshyah, Gehad ElGhazali, Zain Al Yafei, Rami H Al-Rifai, Juma Alkaabi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Raya AlmazroueiDivision of Endocrinology, Tawam Hospital, Al Ain, United Arab Emirates.
Charu SharmaDepartment of Internal Medicine, College of Medicine and Health Sciences, Al Ain, United Arab Emirates University, United Arab Emirates.
Bachar AfandiDivision of Endocrinology, Tawam Hospital, Al Ain, United Arab Emirates.
Khaled M AldahmaniDivision of Endocrinology, Tawam Hospital, Al Ain, United Arab Emirates.
Elhadi H AburawiDepartment of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.ORCID 0000-0001-5200-9048
Salem A BeshyahDepartment of Medicine, Dubai Medical College, Dubai, United Arab Emirates.
Gehad ElGhazaliDepartment of Immunology, Sheikh Khalifa Medical City and Union71/Purehealth, Faculty of Medicine, United Arab Emirates University, Abu Dhabi, United Arab Emirates.
Zain Al YafeiUnion71, Purehealth, Abu Dhabi, United Arab Emirates.
Rami H Al-RifaiInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Juma AlkaabiDepartment of Internal Medicine, College of Medicine and Health Sciences, Al Ain, United Arab Emirates University, United Arab Emirates.ORCID 0000-0003-2477-0408
United Arab Emirates University · AEDubai Medical College · AETawam Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo characterizes Emiratis patients with Type 1 diabetes (T1D) and compares outcomes between continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) users. The WHO-Five Well-Being Index (WHO-5) score was used to screen for depression.

methodsIn this cross-sectional study; sociodemographic, clinical characteristics and insulin replacement regimens were collected on patients with T1D between 2015-2018.

results134 patients with mean age of 20.9±7.5 years were included. Females constitute 56.7% and 50.7% had diabetes duration of >10 years. Diabetic ketoacidosis (DKA) at presentation was reported in 46.3%. Average glycemic control over preceding 12months was satisfactory (less than 7.5%), suboptimal (7.5-9%), and poor (more than 9%) in 26.6%, 42.7% & 30.6% of the patients, respectively. Higher proportion of patients using CSII achieved satisfactory or suboptimal glycemic control compared to patients with MDI (P = 0.003). The latest median /IQR HbA1c was significantly lower (P = 0.041) in patients using CSII (8.2 /1.93%) compared to MDI (8.5/2.45%). There was no significant difference between two groups in DKA, severe hypoglycemia or total WHO-5 score.

conclusionsCSII usage was associated with better glycemic control than MDI, although no difference in DKA and severe hypoglycemia. The overall glycemic control among Emiratis subjects with T1D is unsatisfactory and needs more rigorous patient counseling and education.

Indexed as

Diabetes Mellitus, Type 1Diabetic KetoacidosisHypoglycemiaAdolescentAdultBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinGlycemic ControlHumansHypoglycemic AgentsInjections, SubcutaneousInsulinInsulin Infusion SystemsUnited Arab EmiratesBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulin

Identifiers

PMID36136973
PMCPMC9498969
OpenAlexW4296741272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.