Evidence map›Paper›PMID 36136684›Full record

ArticleVeterinary sciences2022

Serial Measurement of Serum Pancreatic Lipase Immunoreactivity, Feline Trypsin-like Immunoreactivity, and Cobalamin Concentrations in Kittens.

Evangelia M Stavroulaki, Kassiopi Christina G Kokkinaki, Manolis N Saridomichelakis, Jörg M Steiner, Jonathan A Lidbury, Panagiotis G Xenoulis

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Vitamin B12 in Cats: Nutrition, Metabolism, and Disease.Animals : an open access journal from MDPI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Evangelia M StavroulakiClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 224 Trikalon Str., 43132 Karditsa, Greece.ORCID 0000-0002-6710-2074
Kassiopi Christina G KokkinakiClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 224 Trikalon Str., 43132 Karditsa, Greece.ORCID 0000-0003-0286-1982
Manolis N SaridomichelakisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 224 Trikalon Str., 43132 Karditsa, Greece.ORCID 0000-0001-8308-3371
Jörg M SteinerGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX 77843, USA.
Jonathan A LidburyGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX 77843, USA.
Panagiotis G XenoulisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 224 Trikalon Str., 43132 Karditsa, Greece.
University of Thessaly · GRTexas A&M University · US

Funding

Greece and the European Union (European Social Fund- ESF) through the Operational Program «Human Resources Development, Education and Lifelong Learning 2014- 2020 MIS 5048925
6 · The paper itself

Abstract

Serum concentrations of feline pancreatic lipase immunoreactivity (fPLI), feline trypsin-like immunoreactivity (fTLI), and cobalamin are commonly used for the diagnostic investigation of cats with gastrointestinal signs. No information on these parameters in healthy cats less than 1 year of age exists. We aimed to evaluate serum concentrations of fPLI, fTLI, and cobalamin in healthy cats at different time-points during their first 12 months of life. Fourteen healthy 2-month-old kittens were included. Blood was collected at 2, 3, 4, 6, and 12 months of age, and serum concentrations of fPLI, fTLI, and cobalamin were measured. While there was a statistically significant difference in serum fPLI concentrations over time, there was no statistically significant difference between individual time-points. There was no significant difference in serum fTLI concentrations over time. Serum cobalamin concentrations were below the reference interval in 3/13 cats at 2 months of age and were significantly lower by 3 months, when 13/14 had hypocobalaminemia. By 12 months, serum cobalamin had significantly increased, yet 4/12 cats still had hypocobalaminemia. Serum fPLI and fTLI concentrations did not show any statistically or clinically significant differences in young kittens. In contrast, serum cobalamin concentrations were commonly below the reference interval in kittens. Serum fPLI and fTLI concentrations are not practically affected by age in kittens as young as 2 months of age and could be used for the investigation of pancreatic diseases.

Indexed as

B12catexocrine pancreatic insufficiencygastrointestinal diseasepancreatitisPLITLI

Identifiers

PMID36136684
PMCPMC9501717
OpenAlexW4294234620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.