ArticleTropical medicine and infectious disease2022
Impact of COVID-19 on Tuberculosis Indicators in Brazil: A Time Series and Spatial Analysis Study.
Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Geo-spatial high-risk clusters of Tuberculosis in the global general population: a systematic review.BMC public health · 2023Pooled it
- Socioeconomic dynamics and tuberculosis mortality in São Paulo: a population-level analysis using spatial modeling.Lancet regional health. Americas · 2026Article
- Spatiotemporal Patterns and Socioeconomic Determinants of Pulmonary Tuberculosis in Piauí, Northeast Brazil, 2001-2024.Tropical medicine & international health : TM & IH · 2026Article
- Temporal trends in tuberculosis incidence among the aging population in Southwest China: a retrospective study.BMC geriatrics · 2026Article
- Space-time clustering and temporal trend analysis of pulmonary tuberculosis in Brazil, 2010-2023.PloS one · 2026Article
- Projecting tuberculosis control progress in metropolitan and non-metropolitan areas of Brazil, 2001-2035: a Bayesian age-period-cohort analysis.Infectious diseases of poverty · 2025Article
- Systematic differences in TB treatment outcomes across Brazil by patient- and area-related factors: an analysis of national disease registry data.BMJ global health · 2025Article
- The Temporal Trends of Mortality Due to Tuberculosis in Brazil: Tracing the Coronavirus Disease 2019 (COVID-19) Pandemic's Effect Through a Bayesian Approach and Unmasking Disparities.Microorganisms · 2025Article
- Evidence of tuberculosis treatment outcomes among people experiencing homelessness: a scoping review.BMC health services research · 2025Article
- Incidence and mortality by pulmonary tuberculosis in Brazil: Trends and projections, 2002-2034.IJID regions · 2025Article
- Mobile application prototyping using Artificial Intelligence to support childhood tuberculosis diagnosis.Revista brasileira de enfermagem · 2025Article
- Temporal trends in incidence and mortality from pulmonary tuberculosis: time series study, Sul da Bahia, 2010-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Tuberculosis healthcare service disruptions during the COVID-19 pandemic in Brazil, India and South Africa: A model-based analysis of country-level data.PLOS global public health · 2025Article
- BCG vaccination decline and pediatric tuberculosis rise in Brazil: spatial-temporal study.Revista de saude publica · 2025Article
- TB programme outcomes in South Fly District, Papua New Guinea, were maintained through COVID-19.Public health action · 2024Article
- The impact of the COVID-19 pandemic on tuberculosis treatment outcomes in 49 high burden countries.BMC medicine · 2024Article
- The impact of the SARS-CoV-2 pandemic on tuberculosis notifications and deaths in the state of São Paulo, Brazil: a cross-sectional study.Lancet regional health. Americas · 2024Article
- Tuberculosis case notifications and outcomes in Peruvian prisons prior to and during the COVID-19 pandemic: a national-level interrupted time series analysis.Lancet regional health. Americas · 2024Article
- Primary Health Care and Tuberculosis Detection during the COVID-19 Pandemic: Crucial Actions for Intensifying Efforts.International journal of environmental research and public health · 2024Article
- Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic: are we truly advancing toward the sustainable development/end TB goal?Infectious diseases of poverty · 2024Article
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Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundWe aimed to visualize and classify the time series of COVID-19, tuberculosis (TB) notification, and TB outcomes (cure, treatment abandonment, and death), verify the impact of the new coronavirus pandemic on these indices in Brazil, and verify the presence of spatial autocorrelation between COVID-19 and TB.
methodsThis was an ecological time series study that considered TB and COVID-19 cases. Seasonal Trend Decomposition using Loess (STL) was used to trace the temporal trend, Prais-Winsten was used to classify the temporal trend, Interrupted Time Series (ITS) was used to verify the impact of COVID-19 on TB rates, and the Bivariate Moran Index (Global and Local) was used to verify the spatial autocorrelation of events.
resultsBrazil and its macro-regions showed an increasing temporal trend for the notification of TB in the pre-pandemic period. Only the Northeast Region showed a decreasing temporal trend for cured cases. For treatment abandonment, all regions except for the Northeast showed an increasing temporal trend, and regarding death, Brazil and the Northeast Region showed an increasing temporal trend. With the ITS, COVID-19 caused a decline in TB notification rates and TB outcome rates. With the global spatial analysis, it was possible to identify the existence of spatial autocorrelation between the notification rate of COVID-19 and the TB notification rate and deaths. With the local analysis, it was possible to map the Brazilian municipalities and classify them according to the relationship between the rates of both diseases and space.
conclusionsCOVID-19 influenced the follow-up of and adherence to TB treatment and intensified social vulnerability and, consequently, affected the notification of TB since the relationship between the disease and social determinants of health is already known. The restoration and strengthening of essential services for the prevention and detection of cases and treatment of TB in endemic environments such as Brazil have been oriented as a priority in the global health agenda.
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