Evidence map›Paper›PMID 36136551›Full record

ArticleToxins2022

Structure and Biological Properties of Ribosome-Inactivating Proteins and Lectins from Elder (

Rosario Iglesias, Rosita Russo, Nicola Landi, Mariangela Valletta, Angela Chambery, Antimo Di Maro, Andrea Bolognesi, José M Ferreras, Lucía Citores

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  7. MucR fromInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rosario IglesiasDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.ORCID 0000-0002-5021-1733
Rosita RussoDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-2235-6302
Nicola LandiDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Mariangela VallettaDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Angela ChamberyDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-5136-0941
Antimo Di MaroDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-9595-9665
Andrea BolognesiDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum-University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0001-7497-4586
José M FerrerasDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.ORCID 0000-0003-4816-5878
Lucía CitoresDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.ORCID 0000-0003-3784-5042
University of Campania "Luigi Vanvitelli" · ITUniversidad de Valladolid · ESUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ribosome-inactivating proteins (RIPs) are a group of proteins with rRNA N-glycosylase activity that catalyze the removal of a specific adenine located in the sarcin-ricin loop of the large ribosomal RNA, which leads to the irreversible inhibition of protein synthesis and, consequently, cell death. The case of elderberry (

Indexed as

RicinSambucusSambucus nigraAdenineAmino Acid SequenceGalactoseN-Glycosyl HydrolasesPlant LeavesPlant LectinsPlant ProteinsPlantsRibosome Inactivating ProteinsRibosomesRNA, RibosomalAdenineGalactoseN-Glycosyl HydrolasesPlant LectinsPlant ProteinsRibosome Inactivating ProteinsRicinRNA, Ribosomalanticancer agentsgalactoselectinnanoLC–tandem mass spectrometry (nLC-MS/MS)protein synthesis (inhibition)ribosome-inactivating protein (RIP)ricinsugar binding

Identifiers

PMID36136551
PMCPMC9503024
OpenAlexW4294169795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.