ArticleJournal of functional biomaterials2022
A Porous Hydrogel with High Mechanical Strength and Biocompatibility for Bone Tissue Engineering.
Article in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review.Frontiers in bioengineering and biotechnology · 2025Pooled it
- Thermosensitive Hydrogels for Periodontal Regeneration: A Systematic Review of the Evidence.Clinical and experimental dental research · 2024Pooled it
- Physicochemical and Interfacial Insights into Porphyrin-Loaded HPMC Hydrogels.Gels (Basel, Switzerland) · 2026Article
- Baicalein-Cyclodextrin Inclusion Complexes Nasal Thermosensitive Hydrogel: Bioavailability Improvement and Pharmacokinetic Evaluation in Rats.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Cellulose-Based Hydrogels for Chronic Wound Healing: Bridging Biomaterial Design and Clinical Unmet Needs.Gels (Basel, Switzerland) · 2026Review
- Entropy-Regulated Swelling as the Mechanistic Driver of Drug Diffusion in a Mechanically Robust Hydroxyapatite/PVA Hybrid Hydrogel.Macromolecules · 2026Article
- A preliminary feasibility study of a tough hydrogel as a nucleus pulposus substitute for degenerative disc disease.Frontiers in bioengineering and biotechnology · 2026Article
- A review of synergistic strategies in cancer therapy: resveratrol-loaded hydrogels for targeted and multimodal treatment.Discover oncology · 2025Review
- 3D Printing and Property of Biomimetic Hydroxyapatite Scaffold.Biomimetics (Basel, Switzerland) · 2024Article
- Engineering Tough and Elastic Polyvinyl Alcohol-Based Hydrogel with Antimicrobial Properties.Advanced nanobiomed research · 2024Article
- Towards Stem Cell Therapy for Critical-Sized Segmental Bone Defects: Current Trends and Challenges on the Path to Clinical Translation.Journal of functional biomaterials · 2024Review
- Chitosan-Oxidized Pullulan Hydrogels Loaded with Essential Clove Oil: Synthesis, Characterization, Antioxidant and Antimicrobial Properties.Gels (Basel, Switzerland) · 2024Article
- Emerging roles of hydrogel in promoting periodontal tissue regeneration and repairing bone defect.Frontiers in bioengineering and biotechnology · 2024Review
- Sustainable Biomass Lignin-Based Hydrogels: A Review on Properties, Formulation, and Biomedical Applications.International journal of molecular sciences · 2023Review
- Biomechanical Study and Analysis for Cardiovascular/Skeletal Materials and Devices.Journal of functional biomaterials · 2023Article
- Electro-Responsive Conductive Blended Hydrogel Patch.Polymers · 2023Article
- Carbonic Anhydrase Enhanced UV-Crosslinked PEG-DA/PEO Extruded Hydrogel Flexible Filaments and Durable Grids for COGels (Basel, Switzerland) · 2023Article
- Antibacterial, Anti-Biofilm and Pro-Migratory Effects of Double Layered Hydrogels Packaged with Lactoferrin-DsiRNA-Silver Nanoparticles for Chronic Wound Therapy.Pharmaceutics · 2023Article
- Preparation and In Vitro Evaluation of Chitosan-g-Oligolactide Based Films and Macroporous Hydrogels for Tissue Engineering.Polymers · 2023Article
- A study on the material properties of novel PEGDA/gelatin hybrid hydrogels polymerized by electron beam irradiation.Frontiers in chemistry · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Polyvinyl alcohol (PVA) hydrogels are considered to be ideal materials for tissue engineering due to their high water content, low frictional behavior, and good biocompatibility. However, their limited mechanical properties restrict them from being applied when repairing load-bearing tissue. Inspired by the composition of mussels, we fabricated polyvinyl alcohol/hydroxyapatite/tannic acid (PVA/HA/TA) hydrogels through a facile freeze-thawing method. The resulting composite hydrogels exhibited high moisture content, porous structures, and good mechanical properties. The compressive strength and tensile strength of PVA hydrogels were improved from 0.77 ± 0.11 MPa and 0.08 ± 0.01 MPa to approximately 3.69 ± 0.41 MPa and 0.43 ± 0.01 MPa, respectively, for the PVA/HA/1.5TA hydrogel. The toughness and the compressive elastic modulus of PVA/HA/1.5TA hydrogel also attained 0.86 ± 0.02 MJm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.