Evidence map›Paper›PMID 36135290›Full record

ArticleGels (Basel, Switzerland)2022

Nanoemulsion-Based Hydrogels and Organogels Containing Propolis and Dexpanthenol: Preparation, Characterization, and Comparative Evaluation of Stability, Antimicrobial, and Cytotoxic Properties.

Rukiye Sevinç-Özakar, Emrah Seyret, Emrah Özakar, Mehmet Cemal Adıgüzel

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rukiye Sevinç-ÖzakarDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0002-2972-8084
Emrah SeyretFaculty of Pharmacy, Atatürk University, 25240 Erzurum, Turkey.
Emrah ÖzakarDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Atatürk University, 25240 Erzurum, Turkey.
Mehmet Cemal AdıgüzelDepartment of Microbiology, Faculty of Veterinary Medicine, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0002-2385-9649
Atatürk University · TR

Funding

Scientific and Technological Research Council of Turkey 1919B012111399
6 · The paper itself

Abstract

Recently, nanoemulsion-based gels have become very popular for dermal drug delivery, overcoming the disadvantages of conventional semi-solid drug forms. The aim of this study is to prepare and characterize nanoemulsion-based hydrogels and organogels containing combined propolis and dexpanthenol, and to compare their stability, antimicrobial, and cytotoxicity properties. Within the scope of characterization studies, organoleptic properties, drug content, morphology, pH, gel-sol conversion temperature, spreadability, viscosity, FT-IR, and release properties were evaluated in hydrogels and organogels. The characterization studies carried out were subjected to short-term stability evaluation at room temperature and refrigerator for 3 months. While no phase separation was observed in any of the formulations kept in the refrigerator, phase separation was observed in four formulations kept at room temperature. The release study successfully obtained an extended release for propolis and dexpanthenol. In the antimicrobial susceptibility study, Hydrogel 1 showed activity against

Indexed as

antimicrobialcytotoxicitydexpanthenolhydrogelnanoemulsionorganogelpropolisstability

Identifiers

PMID36135290
PMCPMC9498717
OpenAlexW4295886996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.