Evidence map›Paper›PMID 36135287›Full record

ReviewGels (Basel, Switzerland)2022

Intelligent Hydrogels in Myocardial Regeneration and Engineering.

Christian Doescher, An Thai, Ed Cha, Pauline V Cheng, Devendra K Agrawal, Finosh G Thankam

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christian DoescherDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.
An ThaiDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.
Ed ChaDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.
Pauline V ChengDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.
Devendra K AgrawalDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.ORCID 0000-0001-5445-0013
Finosh G ThankamDepartment of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.ORCID 0000-0001-7285-9808
Western University of Health Sciences · US

Funding

Novel Approach to Stabilize Atherosclerotic Plaque in Carotid ArteryR01HL144125 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI AGRAWAL, DEVENDRA K. · 2018 to 2021
$2.8M
Novel Molecular Target to Prevent Maturation Failure of Arteriovenous FistulaR01HL147662 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI AGRAWAL, DEVENDRA K. · 2019 to 2022
$2.8M
NHLBI NIH HHS R01 HL144125NHLBI NIH HHS R01 HL147662
6 · The paper itself

Abstract

Myocardial infarction (MI) causes impaired cardiac function due to the loss of cardiomyocytes following an ischemic attack. Intelligent hydrogels offer promising solutions for post-MI cardiac tissue therapy to aid in structural support, contractility, and targeted drug therapy. Hydrogels are porous hydrophilic matrices used for biological scaffolding, and upon the careful alteration of ideal functional groups, the hydrogels respond to the chemistry of the surrounding microenvironment, resulting in intelligent hydrogels. This review delves into the perspectives of various intelligent hydrogels and evidence from successful models of hydrogel-assisted treatment strategies.

Indexed as

cardiac regenerationintelligent hydrogelsmyocardial infarctiontissue engineering

Identifiers

PMID36135287
PMCPMC9498403
OpenAlexW4295886929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.