ReviewGels (Basel, Switzerland)2022
Hydrogel and Effects of Crosslinking Agent on Cellulose-Based Hydrogels: A Review.
Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 246 citations in OpenAlex.
- Feedstock-Dependent Water Sorption and Retention of Citric-Acid-Modified Lignocellulosic Biogels Under Simulated Climatic Conditions.Gels (Basel, Switzerland) · 2026Article
- Design of a Gelatin/Carboxymethyl Cellulose Hydrogel Containing Myrtus Communis Extract with Anti-inflammatory Capabilities for Accelerated Wound Healing; in Vitro and in Vivo Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Article
- Sustainable Chitosan-Based Biopolymeric Aerogels Reinforced with Activated Carbon, Biochar, Magnesium Oxide and Nanolignin as Bioderived Additives for High-Performance Green Water Sorbents.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Polysaccharide-Based Hydrogel Composites With Organic and Inorganic Fillers: Recent Advances in Reinforcement, Functional Properties, and Selected Applications.ChemSusChem · 2026Review
- Article
- A 25-Year Review of the Use of Silanized Hydroxypropylmethylcellulose Hydrogels in Tissue Engineering and Regenerative Medicine.Macromolecular bioscience · 2026Review
- Biopolymer-Based Hydrogels for Wound Healing: Advances in Cellulose, Chitosan, Alginate, and Hyaluronic Acid from Design to Clinical Translation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Preparation and evaluation of the effect of hydrogel containing Cedrus and mupirocin and application as a wound healing accelerator.Annals of medicine and surgery (2012) · 2026Article
- Tunable PVA-Alginate/FeACS omega · 2026Article
- Cellulose and Its Derivatives in Drug Delivery: Recent Advances and Applications.Pharmaceutics · 2026Review
- CarbopolGels (Basel, Switzerland) · 2026Article
- Cutting-Edge Smart Hydrogel Platforms for Improved Wound Healing.Pharmaceutics · 2026Review
- Crosslinker-Free, Printable Alginate-Boronic Acid Hydrogel Adhesive with Enhanced Mechanical Performance for Soft Tissue Fixation.Molecules (Basel, Switzerland) · 2026Article
- Exosome-loaded hydrogel systems for spinal cord injury repair: mechanisms, advancements, and future directions.Journal of materials science. Materials in medicine · 2026Review
- Design and Application of Stimuli-Responsive Hydrogels for 4D Printing: A Review of Adaptive Materials in Engineering.Gels (Basel, Switzerland) · 2026Review
- Transforming Cellulose for Sustainability: Comprehensive Insights into Modification Approaches and Their Applications.ACS omega · 2026Review
- Hydrogels strategies for organ adhesions: from mechanism to application.Journal of nanobiotechnology · 2026Review
- Selecting Hydrogel Films Composed of Carboxymethyl Cellulose and Microcrystalline Cellulose From OPEFB With Citric Acid as a Green Crosslinker for Fruit Wrapping.International journal of biomaterials · 2026Article
- Properties of novel PBC/κ-carrageenan hydrogels: probiotic bacterial cellulose synthesized by co-culture ofFrontiers in bioengineering and biotechnology · 2026Article
- Eco-Friendly Hydrogels from Natural Gums and Cellulose Citrate: Formulations and Properties.Gels (Basel, Switzerland) · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Hydrogels are hydrophilic polymer materials that can swell but are insoluble in water. Hydrogels can be synthesized with synthetic or natural polymers, but natural polymers are preferred because they are similar to natural tissues, which can absorb a high water content, are biocompatible, and are biodegradable. The three-dimensional structure of the hydrogel affects its water insolubility and ability to maintain its shape. Cellulose hydrogels are preferred over other polymers because they are highly biocompatible, easily accessible, and affordable. Carboxymethyl cellulose sodium (CMCNa) is an example of a water-soluble cellulose derivative that can be synthesized using natural materials. A crosslinking agent is used to strengthen the properties of the hydrogel. Chemical crosslinking agent is used more often than physical crosslinking agent. In this review, article, different types of crosslinking agents are discussed based on synthetic and natural crosslinking agents. Hydrogels that utilize synthetic crosslinking agent have advantages, such as adjustable mechanical properties and easy control of the chemical composition. However, hydrogels that use natural crosslinking agent have better biocompatibility and less latent toxic effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.