Evidence map›Paper›PMID 36135244›Full record

ArticleGels (Basel, Switzerland)2022

Compliant, Tough, Anti-Fatigue, Self-Recovery, and Biocompatible PHEMA-Based Hydrogels for Breast Tissue Replacement Enabled by Hydrogen Bonding Enhancement and Suppressed Phase Separation.

Hongyan Ouyang, Xiangyan Xie, Yuanjie Xie, Di Wu, Xingqi Luo, Jinrong Wu, Yi Wang, Lijuan Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Advanced Hydrogels in Breast Cancer Therapy.Gels (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongyan OuyangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
Xiangyan XieCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
Yuanjie XieCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
Di WuCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
Xingqi LuoCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
Jinrong WuState Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0002-5329-5522
Yi WangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.ORCID 0000-0003-1758-5829
Lijuan ZhaoCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.

Funding

National Natural Science Foundation of China Nos. 51873133 and 51873110the Opening Project of State Key Laboratory of Polymer Materials Engineering (Sichuan University) No. sklpme2022-4-09
6 · The paper itself

Abstract

Although hydrogel is a promising prosthesis implantation material for breast reconstruction, there is no suitable hydrogel with proper mechanical properties and good biocompatibility. Here, we report a series of compliant and tough poly (hydroxyethyl methacrylate) (PHEMA)-based hydrogels based on hydrogen bond-reinforcing interactions and phase separation inhibition by introducing maleic acid (MA) units. As a result, the tensile strength, fracture strain, tensile modulus, and toughness are up to 420 kPa, 293.4%, 770 kPa, and 0.86 MJ/m

Indexed as

biocompatibilitybreast reconstructionhydrogen bond enhancementphase separation inhibitionPHEMA-based hydrogel

Identifiers

PMID36135244
PMCPMC9498755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.