Evidence map›Paper›PMID 36134940›Full record

ArticleBiomimetics (Basel, Switzerland)2022

Effects of rmBMP-7 on Osteoblastic Cells Grown on a Nanostructured Titanium Surface.

Leonardo Raphael Zuardi, Fabíola Singaretti de Oliveira, Roger Rodrigo Fernandes, Maria Paula Oliveira Gomes, Silvia Spriano, Antonio Nanci, Paulo Tambasco de Oliveira

Open access · goldAbstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Leonardo Raphael ZuardiDepartment of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-5782-9114
Fabíola Singaretti de OliveiraDepartment of Oral and Maxillofacial Surgery and Periodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.
Roger Rodrigo FernandesDepartment of Oral and Maxillofacial Surgery and Periodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-9245-1823
Maria Paula Oliveira GomesDepartment of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-4466-0794
Silvia SprianoDepartment of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0002-7367-9777
Antonio NanciFaculté de Médecine Dentaire, Université de Montréal, Montreal, QC H3T 1J4, Canada.ORCID 0000-0003-0616-843X
Paulo Tambasco de OliveiraDepartment of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-6662-0486
Universidade de São Paulo · BRPolitecnico di Torino · ITUniversité de Montréal · CA

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 1569214National Council for Scientific and Technological Development 157332/2017-9National Council for Scientific and Technological Development 315266/2020-1São Paulo Research Foundation 2016/50298-4
6 · The paper itself

Abstract

This study evaluates the effects of the availability of exogenous BMP-7 on osteoblastic cells' differentiation on a nanotextured Ti surface obtained by chemical etching (Nano-Ti). The MC3T3-E1 and UMR-106 osteoblastic cell lines were cultured for 5 and 7 days, respectively, on a Nano-Ti surface and on a control surface (Control-Ti) in an osteogenic medium supplemented with either 40 or 200 ng/mL recombinant mouse (rm) BMP-7. The results showed that MC3T3-E1 cells exhibited distinct responsiveness when exposed to each of the two rmBMP-7 concentrations, irrespective of the surface. Even with 40 ng/mL rmBMP-7, important osteogenic effects were noticed for Control-Ti in terms of cell proliferation potential;

Indexed as

BMP-7nanotopographyosteoblasttitanium

Identifiers

PMID36134940
PMCPMC9496167
OpenAlexW4296312339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.