Evidence map›Paper›PMID 36134576›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

A Cascade Sonogashira Cross-Coupling-Substitution-Elimination Reaction for the Synthesis of Linear Conjugated Dienynes.

Alejandro Lumbreras-Teijeiro, Matea Bacic, Judit Oliver-Meseguer, Antonio Leyva-Pérez

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro Lumbreras-TeijeiroInstituto de Tecnología Química (UPV-CSIC), Universidad Politècnica de València-Consejo Superior de Investigaciones Científicas, Avda. de los Naranjos s/n, 46022, Valencia, Spain.
Matea BacicInstituto de Tecnología Química (UPV-CSIC), Universidad Politècnica de València-Consejo Superior de Investigaciones Científicas, Avda. de los Naranjos s/n, 46022, Valencia, Spain.
Judit Oliver-MeseguerInstituto de Tecnología Química (UPV-CSIC), Universidad Politècnica de València-Consejo Superior de Investigaciones Científicas, Avda. de los Naranjos s/n, 46022, Valencia, Spain.
Antonio Leyva-PérezInstituto de Tecnología Química (UPV-CSIC), Universidad Politècnica de València-Consejo Superior de Investigaciones Científicas, Avda. de los Naranjos s/n, 46022, Valencia, Spain.

Funding

Conselleria de Cultura, Educación y Ciencia, Generalitat Valenciana GV/2021/138Ministerio de Ciencia e Innovación IJC2018-036514-IMinisterio de Ciencia e Innovación PID2020-115100GB-I00Ministerio de Ciencia e Innovación PRE2020-093338
6 · The paper itself

Abstract

The engagement in tandem of well-known organic reactions such as the Pd-catalyzed Sonogashira cross-coupling reaction, nucleophilic substitution and elimination reactions, enables the synthesis of otherwise difficult to obtain linear dienynes, in moderate to high yields. This retrosynthetic approach opens new ways to prepare highly conjugated alkenes and alkynes. Furthermore, ionic liquids are suitable solvents to perform the cascade reaction and recycle the metal catalysts.

Indexed as

Ionic LiquidsPalladiumAlkynesCatalysisSolventsAlkynesIonic LiquidsPalladiumSolventscascade reactioncross-couplingdienyneseliminationionic liquidssubstitution

Identifiers

PMID36134576
PMCPMC10092193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.