ArticleThe Journal of international medical research2022
Hematological and molecular analyses of the HbS allele among the Sudanese population.
Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 1 citations in OpenAlex.
- ß-Globin gene cluster haplotypes in Moroccan sickle cell disease patients: diversity pilot study.African health sciences · 2026Article
- Molecular Detection of Hemoglobin O-Arab in the Sudanese Population.International journal of general medicine · 2023Article
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Authors and funding
8 authors at 3 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to perform hematological and molecular analyses of the HbS allele of the hemoglobin subunit beta gene in the Sudanese population.
methodsThis was a descriptive cross-sectional study. Hematological parameters and fetal hemoglobin (HbF) levels were assessed in all participants. Data were gathered through the use of questionnaires and laboratory investigations. The β
resultsAccording to our findings, the Bantu (BA) haplotype was found in 10.8% of participants with homozygous uncontested haplotypes, followed by Benin (BA) and Sudan (SU), each in 9.8% of participants. This Sudanese group from Northern Kordofan lacked the Arab-Indian haplotype. Two heterozygous versions of undisputed haplotypes were found in 17.3% of participants: SU/BA in 10.8% and CA/BE in 6.5%.
conclusionAs a result of sickle cell anemia, this investigation found changes in hematological parameters. In the Sudanese population, a new haplotype of the S gene was discovered.
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