Evidence map›Paper›PMID 36134351›Full record

ArticleNanoscale advances2022

Tracking the fates of iron-labeled tumor cells

Ashley V Makela, Melissa A Schott, Olivia C Sehl, Julia J Gevaert, Paula J Foster, Christopher H Contag

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Magnetic nanoparticles for cancer theranostics.Biomedical physics & engineering express · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Machine Learning and Deep Learning Applications in Magnetic Particle Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. A primer onFrontiers in medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ashley V MakelaMichigan State University, Institute for Quantitative Health Science and Engineering East Lansing MI USA contagch@msu.edu.ORCID https://orcid.org/0000-0002-2048-6832
Melissa A SchottMichigan State University, Institute for Quantitative Health Science and Engineering East Lansing MI USA contagch@msu.edu.
Olivia C SehlWestern University, Robarts Research Institute, Department of Medical Biophysics London ON Canada.
Julia J GevaertWestern University, Robarts Research Institute, Department of Medical Biophysics London ON Canada.ORCID https://orcid.org/0000-0002-2918-6617
Paula J FosterWestern University, Robarts Research Institute, Department of Medical Biophysics London ON Canada.
Christopher H ContagMichigan State University, Institute for Quantitative Health Science and Engineering East Lansing MI USA contagch@msu.edu.
Michigan State University · USWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of imaging to detect and monitor the movement and accumulation of cells in living subjects can provide significant insights that can improve our understanding of metastasis and guide therapeutic development. For cell tracking using Magnetic Resonance Imaging (MRI), cells are labeled with iron oxides and the effects of the iron on water provides contrast. However, due to low specificity and difficulties in quantification with MRI, other modalities and approaches need to be developed. Magnetic Particle Imaging (MPI) is an emerging imaging technique which directly detects iron, allowing for a specific, quantitative and sensitive readout. Here, we use MPI to image iron-labeled tumor cells longitudinally, from implantation and growth at a primary site to movement to distant anatomic sites.

Identifiers

PMID36134351
PMCPMC9400501
OpenAlexW4287385011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.