Evidence map›Paper›PMID 36134176›Full record

ReviewNanoscale advances2021

Gold nanomaterials for optical biosensing and bioimaging.

Peng Si, Nasrin Razmi, Omer Nur, Shipra Solanki, Chandra Mouli Pandey, Rajinder K Gupta, Bansi D Malhotra, Magnus Willander, Adam de la Zerda

Open access · goldAbstract readReview
In one paragraph

Review in Nanoscale advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 195 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Peng SiDepartment of Structural Biology, Stanford University California 94305 USA adlz@stanford.edu.ORCID https://orcid.org/0000-0003-2596-8360
Nasrin RazmiDepartment of Science and Technology, Physics and Electronics, Linköping University SE-60174 Norrköping Sweden magnus.willander@liu.se.
Omer NurDepartment of Science and Technology, Physics and Electronics, Linköping University SE-60174 Norrköping Sweden magnus.willander@liu.se.ORCID https://orcid.org/0000-0002-2467-745X
Shipra SolankiDepartment of Biotechnology, Delhi Technological University Shahbad Daulatpur Delhi 110042 India.
Chandra Mouli PandeyDepartment of Applied Chemistry, Delhi Technological University Shahbad Daulatpur Delhi 110042 India.ORCID https://orcid.org/0000-0003-0079-0586
Rajinder K GuptaDepartment of Applied Chemistry, Delhi Technological University Shahbad Daulatpur Delhi 110042 India.
Bansi D MalhotraDepartment of Biotechnology, Delhi Technological University Shahbad Daulatpur Delhi 110042 India.ORCID https://orcid.org/0000-0002-0957-2684
Magnus WillanderDepartment of Science and Technology, Physics and Electronics, Linköping University SE-60174 Norrköping Sweden magnus.willander@liu.se.
Adam de la ZerdaDepartment of Structural Biology, Stanford University California 94305 USA adlz@stanford.edu.
Delhi Technological University · INLinköping University · SEStanford University · US

Funding

Pilot ProjectsU54CA151459 · NCI · STANFORD UNIVERSITY · PI GAMBHIR, SANJIV S · 2010 to 2014
$12.6M
NCI NIH HHS U54 CA151459
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) are highly compelling nanomaterials for biomedical studies due to their unique optical properties. By leveraging the versatile optical properties of different gold nanostructures, the performance of biosensing and biomedical imaging can be dramatically improved in terms of their sensitivity, specificity, speed, contrast, resolution and penetration depth. Here we review recent advances of optical biosensing and bioimaging techniques based on three major optical properties of AuNPs: surface plasmon resonance, surface enhanced Raman scattering and luminescence. We summarize the fabrication methods and optical properties of different types of AuNPs, highlight the emerging applications of these AuNPs for novel optical biosensors and biomedical imaging innovations, and discuss the future trends of AuNP-based optical biosensors and bioimaging as well as the challenges of implementing these techniques in preclinical and clinical investigations.

Identifiers

PMID36134176
PMCPMC9418567
OpenAlexW3155174656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.