Evidence map›Paper›PMID 36134125›Full record

ArticleCancer research communications2022

Serum carotenoids and cancer-related fatigue: An analysis of the 2005-2006 National Health and Nutrition Examination Survey.

Amber S Kleckner, Edwin van Wijngaarden, Todd A Jusko, Ian R Kleckner, Po-Ju Lin, Karen M Mustian, Luke J Peppone

Open access · goldAbstract read
In one paragraph

Article in Cancer research communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amber S KlecknerDepartment of Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, 21201.
Edwin van WijngaardenDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, New York, 14642.
Todd A JuskoDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, New York, 14642.
Ian R KlecknerDepartment of Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, 21201.
Po-Ju LinDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, New York, 14642.
Karen M MustianDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, New York, 14642.
Luke J PepponeDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, New York, 14642.
University of Rochester Medical Center · USUniversity of Maryland, Baltimore · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI B Paige Lawrence · 1985 to 2026
$42.8M
NRSA Training CoreTL1TR002000 · NCATS · UNIVERSITY OF ROCHESTER · PI THAKAR, JUILEE, VAN WIJNGAARDEN, EDWIN · 2016 to 2024
$4.1M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
Treatment of Refractory NauseaR01CA200579 · NCI · UNIVERSITY OF ROCHESTER · PI PEPPONE, LUKE JOSEPH · 2016 to 2021
$1.1M
The Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy, Inflammation, and Interoceptive Brain CircuitryK07CA221931 · NCI · UNIVERSITY OF ROCHESTER · PI KLECKNER, IAN ROBERT · 2018 to 2022
$795k
NCATS NIH HHS TL1 TR002000NCI NIH HHS K07 CA221931NCI NIH HHS R01 CA200579NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

Cancer-related fatigue is a prevalent, debilitating condition, and preliminary evidence suggests a relationship between higher diet quality and lower fatigue. Serum-based carotenoids, Vitamin A, and Vitamin E are biomarkers of fruit and vegetable intake and therefore diet quality. To further elucidate the link between diet quality and cancer-related fatigue, associations were assessed between these serum-based nutrients and fatigue among American adults with special attention to cancer history. Data were analyzed from the United States 2005-2006 National Health and Nutrition Examination Survey (NHANES) dataset. Ten carotenoids, vitamin A, vitamin E, and γ-tocopherol were measured from fasting blood samples and fatigue was patient-reported. Associations between carotenoid concentration and fatigue were estimated using ordinal logistic regression models. Adjusted models included a diagnosis of cancer (with the exception on non-melanoma skin cancer, yes/no), age, body mass index, race/ethnicity, education, and exercise habits as covariates, and additional models included a cancer×nutrient interaction. Of 4091 participants, 272 (8.0%) reported a history of cancer. Greater fatigue was associated with lower serum

Indexed as

CarotenoidsNeoplasmsAdultBiomarkersFatigueHumansNutrition SurveysUnited StatesVegetablesVitamin AVitamin EBiomarkersCarotenoidsVitamin AVitamin Ecancer-related fatiguecarotenoidsfatigueNHANESnutritionsurvivorship

Identifiers

PMID36134125
PMCPMC9489051
OpenAlexW4221086997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.