Evidence map›Paper›PMID 36134086›Full record

ReviewCureus2022

Immediate Versus Salvage Postoperative Radiotherapy in High-Risk Prostate Cancer Patients: A Critical Review.

Soufiane Berhili, Mohammed Amine Guerrouaz, Fatima Zahra Terrab, Mohammed Moukhlissi, Loubna Mezouar

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Soufiane BerhiliRadiation Oncology, Faculty of Medicine, Mohammed First University, Oujda, MAR.
Mohammed Amine GuerrouazRadiation Therapy, Centre Hospitalier Universitaire Mohammed Vi, Oujda, MAR.
Fatima Zahra TerrabRadiation Oncology, Hassan II Center of Oncology, Mohammed VI University Hospital, Oujda, MAR.
Mohammed MoukhlissiRadiation Oncology, Faculty of Medicine, Mohammed First University, Oujda, MAR.
Loubna MezouarRadiation Oncology, Faculty of Medicine, Mohammed First University, Oujda, MAR.
Centre Hospitalier Universitaire Mohammed VI · MAMohamed I University · MAUniversité Hassan II Mohammedia · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical prostatectomy in high-risk prostate cancer patients has long been followed by immediate adjuvant radiotherapy (IART) to increase biochemical relapse-free survival. However, the increased urinary and digestive radio-induced toxicities have raised questions about the safety of delaying radiotherapy until the occurrence of biochemical or clinical relapse. Recently, early salvage radiotherapy (ESRT) has been compared to IART, and results found equivalence in terms of efficiency outcomes, but increased toxicity was noted in patients receiving IART, leading to the proposal of ESRT as the new standard of care in high-risk patients after surgery. However, several confounding points are discussed in the present review regarding the methodology and results of these recent trials. Further follow-up is necessary to detect possible long-term advantages of one radiotherapy timing over the other.

Indexed as

early salvage radiotherapyhigh-risk prostate cancerimmediate adjuvant radiotherapyoutcomesradical prostatectomy

Identifiers

PMID36134086
PMCPMC9481222
OpenAlexW4289782325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.