Evidence map›Paper›PMID 36133907›Full record

ArticleFrontiers in molecular biosciences2022

A non-synonymous single nucleotide polymorphism in

Layne N Rodden, Christian Rummey, Yi Na Dong, Sarah Lagedrost, Sean Regner, Alicia Brocht, Khalaf Bushara, Martin B Delatycki, Christopher M Gomez, Katherine Mathews and 13 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 3 countries.

Layne N RoddenDepartments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Christian RummeyClinical Data Science GmbH, Basel, Switzerland.
Yi Na DongDepartments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Sarah LagedrostDepartments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Sean RegnerDepartments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Alicia BrochtUniversity of Rochester, Rochester, NY, United States.
Khalaf BusharaUniversity of Minnesota, Minneapolis, MN, United States.
Martin B DelatyckiMurdoch Children's Research Institute, Victorian Clinical Genetics Services, Melbourne, VIC, Australia.
Christopher M GomezDepartment of Neurology, The University of Chicago, Chicago, IL, United States.
Katherine MathewsDepartments of Pediatrics and Neurology, University of Iowa Carver College of Medicine, Iowa City, IA, United States.
Sarah MurrayDepartment of Pathology, School of Medicine, University of California, San Diego, San Diego, CA, United States.
Susan PerlmanDepartment of Neurology, University of California, Los Angeles, Los Angeles, CA, United States.
Bernard RavinaPraxis Precision Medicines, Boston, MA, United States.
S H SubramonyDepartment of Neurology, University of Florida, College of Medicine, Gainesville, FL, United States.
George WilmotDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, United States.
Theresa ZesiewiczDepartment of Neurology, University of South Florida, Tampa, FL, United States.
Alessandra BolottaThe Scripps Research Institute, La Jolla, CA, United States.
Alain DomissyThe Scripps Research Institute, La Jolla, CA, United States.
Christine JespersenThe Scripps Research Institute, La Jolla, CA, United States.
Baohu JiThe Scripps Research Institute, La Jolla, CA, United States.
Elisabetta SoragniThe Scripps Research Institute, La Jolla, CA, United States.
Joel M GottesfeldThe Scripps Research Institute, La Jolla, CA, United States.
David R LynchDepartments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Scripps Research Institute · USUniversity of Pennsylvania · USChildren's Hospital of Philadelphia · USEmory University · USFlorida College · USMurdoch Children's Research Institute · AUPraxis (United States) · USSwiss Data Science Center · CHUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of Chicago · USUniversity of Iowa · USUniversity of Minnesota · USUniversity of Rochester · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ataxiaclinical trialepigeneticmitochondrionmodifiermRNA profilingSIRT6

Identifiers

PMID36133907
PMCPMC9483148
OpenAlexW4294617548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.