Evidence map›Paper›PMID 36133892›Full record

ArticleNanoscale advances2020

Mass spectrometry imaging and monitoring of

Arthur C K Chung, Xuan Li, Wai-Chung Li, Tao Wang, Hin-Kiu Lee, Lijian Jin, Zongwei Cai, Ken Cham-Fai Leung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Pharmacokinetic and tissue distribution advantages of intraperitoneal oxaliplatin over systemic delivery: a swine model comparison of PIPAC and HPIPAC.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  2. Janus and Amphiphilic MoSSmall methods · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Arthur C K ChungDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.
Xuan LiFaculty of Dentistry, The University of Hong Kong Sai Ying Pun Hong Kong SAR P. R. China.
Wai-Chung LiDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.
Tao WangDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.
Hin-Kiu LeeDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.
Lijian JinFaculty of Dentistry, The University of Hong Kong Sai Ying Pun Hong Kong SAR P. R. China.ORCID https://orcid.org/0000-0002-5340-9710
Zongwei CaiDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.ORCID https://orcid.org/0000-0002-8724-7684
Ken Cham-Fai LeungDepartment of Chemistry, State Key Laboratory of Environmental and Biological Analysis, The Hong Kong Baptist University Kowloon Tong Kowloon Hong Kong SAR P. R. China cfleung@hkbu.edu.hk zwcai@hkbu.edu.hk.ORCID https://orcid.org/0000-0002-0349-0418
Hong Kong Baptist University · HKFaculty (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing number of studies have reported the use of various nanoparticles to encapsulate cisplatin, a frontline chemotherapeutic drug against a broad-spectrum of cancers, for overcoming its inherent drawbacks in clinical applications. Nevertheless, few analytical methods or instruments could provide the precise distribution information on this platinum drug in biological tissues. Herein, we provide the first evidence of applying matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) to assess the spatial distribution of cisplatin released from the cell-penetrating poly(disulfide) (CPD)-modified hollow iron oxide nanoparticles (hFe

Identifiers

PMID36133892
PMCPMC9416930
OpenAlexW3097721398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.