Evidence map›Paper›PMID 36133757›Full record

ArticleNanoscale advances2021

Graphene based electrochemical immunosensor for the ultra-sensitive label free detection of Alzheimer's beta amyloid peptides Aβ(1-42).

Hina Y Abbasi, Zari Tehrani, Anitha Devadoss, Muhammad Munem Ali, Soraya Moradi-Bachiller, Diego Albani, Owen J Guy

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Hina Y AbbasiCentre for NanoHealth, College of Engineering, Swansea University Swansea SA2 8PP UK h.y.abbasi@swansea.ac.uk o.j.guy@swansea.ac.uk +44 (0) 1792 606475 +44 (0) 1792 513181.ORCID https://orcid.org/0000-0001-8818-3048
Zari TehraniCentre for NanoHealth, College of Engineering, Swansea University Swansea SA2 8PP UK h.y.abbasi@swansea.ac.uk o.j.guy@swansea.ac.uk +44 (0) 1792 606475 +44 (0) 1792 513181.ORCID https://orcid.org/0000-0002-5069-7921
Anitha DevadossCentre for NanoHealth, College of Engineering, Swansea University Swansea SA2 8PP UK h.y.abbasi@swansea.ac.uk o.j.guy@swansea.ac.uk +44 (0) 1792 606475 +44 (0) 1792 513181.
Muhammad Munem AliCentre for NanoHealth, College of Engineering, Swansea University Swansea SA2 8PP UK h.y.abbasi@swansea.ac.uk o.j.guy@swansea.ac.uk +44 (0) 1792 606475 +44 (0) 1792 513181.ORCID https://orcid.org/0000-0001-9151-4194
Soraya Moradi-BachillerDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS Via La Masa 19 20156 Milan Italy.ORCID https://orcid.org/0000-0002-1982-737X
Diego AlbaniDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS Via La Masa 19 20156 Milan Italy.
Owen J GuyCentre for NanoHealth, College of Engineering, Swansea University Swansea SA2 8PP UK h.y.abbasi@swansea.ac.uk o.j.guy@swansea.ac.uk +44 (0) 1792 606475 +44 (0) 1792 513181.
Swansea University · GBMario Negri Institute for Pharmacological Research · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An immunosensor capable of high sensitivity detection of beta-amyloid peptides, shown to be a reliable biomarker for Alzheimer's disease, has been developed using screen printed graphene electrodes (SPGEs) modified with ultra-thin layers of polymerised 1,5-diaminonaphthalene (pDAN). Electropolymerization of 1,5-diaminonaphthalene (DAN) was performed to coat the graphene screen printed electrodes in a continuous polymer layer with controlled thickness. The surface characteristics of pristine graphene and polymer modified graphene electrodes were examined using Raman and X-ray photoelectron spectroscopy. The effects of polymer thickness on the electron transfer rates were investigated. An immunosensor for selective detection of beta amyloid peptides Aβ(1-42) was developed

Identifiers

PMID36133757
PMCPMC9419744
OpenAlexW3130490250

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.