ArticleNanoscale advances2019
Fluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring.
Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Multi-Response Optimization of Processing Parameters for Micro-Pockets on Alumina Bioceramic Using Rotary Ultrasonic Machining.Materials (Basel, Switzerland) · 2020Article
- Advances in Optical Biosensors and Sensors Using Nanoporous Anodic Alumina.Sensors (Basel, Switzerland) · 2020Review
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Authors and funding
9 authors.
Funding
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Abstract
In this paper, we demonstrate a simple yet effective hybrid method to fabricate lab-on-a-chip devices on aluminum (Al) foil. Instead of using conventional photoresists and lithography methods, an array of square units is first produced by femtosecond laser direct writing, followed by generating highly ordered anodized aluminum oxide (AAO) nanoporous structures within each unit. The AAO treated area becomes hydrophilic. Next, we functionalize the surrounding area outside the square units to superhydrophobic by electrochemical deposition and further chemical modification. This hydrophilic and hydrophobic pattern allows us to confine the liquid samples to be detected within the hydrophilic AAO detection area. We use rhodamine 6G (R6G) as a probe, and obtain a fluorescence intensity enhancement from R6G by 70 times over a flat surface. This leads to the detection sensitivity of R6G molecules to a concentration as low as 10
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