Evidence map›Paper›PMID 36133531›Full record

ArticleNanoscale advances2019

Relationship between structure and molecular interactions in monolayers of specially designed aminolipids.

Cristina Stefaniu, Christian Wölk, Gerald Brezesinski, Emanuel Schneck

Abstract read
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristina StefaniuDepartments of Biomaterials and Biomolecular Systems, Max Planck Institute of Colloids and Interfaces Am Mühlenberg 1 14476 Potsdam Germany stefaniu@mpikg.mpg.de.
Christian WölkInstitute of Pharmacy, Research Group Biochemical Pharmacy, Martin-Luther-University Wolfgang-Langenbeck-Strasse 4 06120 Halle (Saale) Germany.ORCID https://orcid.org/0000-0002-8067-7307
Gerald BrezesinskiDepartments of Biomaterials and Biomolecular Systems, Max Planck Institute of Colloids and Interfaces Am Mühlenberg 1 14476 Potsdam Germany stefaniu@mpikg.mpg.de.ORCID https://orcid.org/0000-0003-1684-1157
Emanuel SchneckDepartments of Biomaterials and Biomolecular Systems, Max Planck Institute of Colloids and Interfaces Am Mühlenberg 1 14476 Potsdam Germany stefaniu@mpikg.mpg.de.ORCID https://orcid.org/0000-0001-9769-2194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial cationic lipids are already recognized as highly efficient gene therapy tools. Here, we focus on another potential use of aminolipids, in their electrically-uncharged state, for the formation of covalently cross-linked, one-molecule-thin films at interfaces. Such films are envisioned for future (bio-)materials applications. To this end, Langmuir monolayers of structurally different aminolipids are comprehensively characterized with the help of highly sensitive surface characterization techniques. Pressure-area isotherms, Brewster angle microscopy, grazing-incidence X-ray diffraction and infrared reflection-absorption spectrometry experiments provide a detailed, comparative molecular picture of the formed monolayers. This physico-chemical study highlights the relationship between chemical structures and intermolecular interactions, which can serve as a basis for the rational design of cross-linked thin films with precisely controlled properties.

Identifiers

PMID36133531
PMCPMC9418614

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.