Evidence map›Paper›PMID 36133506›Full record

ArticleCureus2022

Scrub Typhus Meningoencephalitis: An Overlooked Entity.

Ashutosh Upadhyaya, Mohammad R Alam, Ali Akbar Raeen, Shriya Upadhyaya, Monika Pathania, Susmita Upadhyaya, Kumarasamy Sivanu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ashutosh UpadhyayaMedicine, Evergreen Hospital Pvt. Ltd, Parasi, NPL.
Mohammad R AlamInternal Medicine, Argakhachi District Hospital, Argakhachhi, NPL.
Ali Akbar RaeenInternal Medicine, Institute of Medicine (IOM) Tribhuvan University Teaching Hospital (TUTH), Kathmandu, NPL.
Shriya UpadhyayaMedicine, Evergreen Hospital Pvt. Ltd, Parasi, NPL.
Monika PathaniaInternal Medicine, All India Institute of Medical Sciences, Rishikesh, IND.
Susmita UpadhyayaInternal Medicine, All India Institute of Medical Sciences, Rishikesh, IND.
Kumarasamy SivanuInternal Medicine, Milton Keynes University Hospital, University of Buckingham, Buckingham, GBR.
All India Institute of Medical Sciences RishikeshMilton Keynes Hospital · GBTribhuvan University Teaching Hospital · NPUniversity of Buckingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scrub typhus is common in rural parts of Nepal, but its diagnosis remains difficult due to a lack of clinical suspicion and poor diagnostic resources. The absence of common clinical features further complicates this problem. Acute kidney injury (AKI), myocarditis, rhabdomyolysis, hepatitis, acute respiratory distress syndrome, and meningoencephalitis are complications of the disease associated with high mortality. Overlap findings can be noted in scrub typhus meningoencephalitis and other tropical infections. This makes diagnosing the disease more challenging, especially in areas where the burden of infectious diseases is high. We report three cases of scrub typhus meningoencephalitis. All three patients were treated successfully with doxycycline. Because patients with scrub typhus have an excellent response to treatment, delay in treatment and rate of complications can be prevented with high clinical suspicion of the condition.

Indexed as

acute encephalitis syndromemeningoencephalitisorientia tsutsugamushiscrub typhustropical fever

Identifiers

PMID36133506
PMCPMC9471502
OpenAlexW4295296647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.