ArticleRevista panamericana de salud publica = Pan American journal of public health2022
Association between population hypertension control and ischemic heart disease and stroke mortality in 36 countries of the Americas, 1990-2019: an ecological study.
Article in Revista panamericana de salud publica = Pan American journal of public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 22 citations in OpenAlex.
- The burden of noncommunicable and injury-related nervous system disorders in the Americas, 1990-2023: an analysis of the Global Burden of Disease Study 2023.Lancet regional health. Americas · 2026Article
- Scaling integrated cardiovascular-kidney-metabolic care through primary health care in the Americas: a health policy analysis of HEARTS 2.0 implementation levers and architecture.Lancet regional health. Americas · 2026Review
- Prevalence and Determinants of Uncontrolled Hypertension Among Treated Adults in a Rural Primary Health Care Facility in South Africa: A Cross-Sectional Study.Epidemiologia (Basel, Switzerland) · 2026Article
- Changes in Cardiometabolic Risk Factors and Ischaemic Heart Disease Mortality Between 2000 and 2015: A Global Ecological Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Economic impact of standardized hypertension treatment on household income in Argentina: a longitudinal analysis, 2019-2024.Revista panamericana de salud publica = Pan American journal of public health · 2026Article
- HEARTS Accreditation: institutionalizing quality improvement of integrated cardiovascular, kidney, and metabolic services in primary care.Revista panamericana de salud publica = Pan American journal of public health · 2026Article
- Translating Guidelines, Protocols, and Care Pathways for Hypertension Into Effective Program Implementation.American journal of hypertension · 2026Article
- HEARTS quality: a policy framework to strengthen hypertension and cardiovascular risk management in primary healthcare-insights from HEARTS in the Americas.Lancet regional health. Americas · 2026Review
- Pilot Study Assessing the Hemodynamic Impact and Post-Exercise Hypotension Induced by High- Versus Low-Intensity Isometric Handgrip in Patients with Ischemic Heart Disease.Journal of cardiovascular development and disease · 2025Article
- Reducing inequalities in cardiovascular disease: focus on marginalized populations considering ethnicity and race.The Lancet regional health. Europe · 2025Review
- Cardiovascular diseaseLancet regional health. Americas · 2025Article
- Risk and impact of stroke across 38 countries and territories of the Americas from 1990 to 2021: a population-based trends analysis from the Global Burden of Disease Study 2021.Lancet regional health. Americas · 2025Article
- Correlation of peripheral blood pressure with central blood pressure and estimation of central blood pressure thresholds for diagnosis of hypertension during pregnancy.Frontiers in medicine · 2025Article
- Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1.Global heart · 2025Article
- Article
- HEARTS in the Americas: Targeting Health System Change to Improve Population Hypertension Control.Current hypertension reports · 2024Review
- Ischemic heart disease-related mortality in Brazil, 2006 to 2020. A study of multiple causes of death.BMC public health · 2024Article
- Barriers to access to antihypertensive medicines: insights from the HEARTS initiative in latin American and Caribbean region.Journal of pharmaceutical policy and practice · 2024Article
- [Evaluation of Implementation of the HEARTS Initiative in a Rural Community in Venezuela, 2023Avaliação da implementação da iniciativa HEARTS em uma comunidade rural da Venezuela, 2023].Revista panamericana de salud publica = Pan American journal of public health · 2024Article
- Burden of undiagnosed hypertension and its associated factors: A challenge for primary health care in urban Colombia.PloS one · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To quantify the association between the prevalence of population hypertension control and ischemic heart disease (IHD) and stroke mortality in 36 countries of the Americas from 1990 to 2019. Methods: This ecologic study uses the prevalence of hypertension, awareness, treatment, and control from the NCD-RisC and IHD and stroke mortality from the Global Burden of Disease Study 2019. Regression analysis was used to assess time trends and the association between population hypertension control and mortality. Results: Between 1990 and 2019, age-standardized death rates due to IHD and stroke declined annually by 2.2% (95% confidence intervals: -2.4 to -2.1) and 1.8% (-1.9 to -1.6), respectively. The annual reduction rate in IHD and stroke mortality deaccelerated to -1% (-1.2 to -0.8) during 2000-2019. From 1990 to 2019, the prevalence of hypertension controlled to a systolic/diastolic blood pressure ≤140/90 mmHg increased by 3.2% (3.1 to 3.2) annually. Population hypertension control showed an inverse association with IHD and stroke mortality, respectively, regionwide and in all but 3 out of 36 countries. Regionwide, for every 1% increase in population hypertension control, our data predicted a reduction of 2.9% (-2.94 to -2.85) in IHD deaths per 100 000 population, equivalent to an averted 25 639 deaths (2.5 deaths per 100 000 population) and 2.37% (-2.41 to -2.33) in stroke deaths per 100 000 population, equivalent to an averted 9 650 deaths (1 death per 100 000 population). Conclusion: There is a strong ecological negative association between IHD and stroke mortality and population hypertension control. Countries with the best performance in hypertension control showed better progress in reducing CVD mortality. Prediction models have implications for hypertension management in most populations in the Region of the Americas and other parts of the world.
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