Evidence map›Paper›PMID 36133340›Full record

ReviewNanoscale advances2022

Effects of polymer carriers on the occurrence and development of autophagy in drug delivery.

Changduo Wang, Yang Li, Yu Tian, Wenyuan Ma, Yong Sun

Open access · goldAbstract readReview
In one paragraph

Review in Nanoscale advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Changduo WangDepartment of Pharmaceutics, School of Pharmacy, Qingdao University Qingdao 266000 China sunyong@qdu.edu.cn +86-532-82991203.
Yang LiDepartment of Pharmacy, Qingdao Municipal Hospital Qingdao 266000 China.
Yu TianDepartment of Pharmaceutics, School of Pharmacy, Qingdao University Qingdao 266000 China sunyong@qdu.edu.cn +86-532-82991203.
Wenyuan MaDepartment of Pharmaceutics, School of Pharmacy, Qingdao University Qingdao 266000 China sunyong@qdu.edu.cn +86-532-82991203.
Yong SunDepartment of Pharmaceutics, School of Pharmacy, Qingdao University Qingdao 266000 China sunyong@qdu.edu.cn +86-532-82991203.ORCID https://orcid.org/0000-0003-0365-1151
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is an evolutionarily conserved catabolic process that can degrade cytoplasmic materials and recycle energy to maintain metabolite homeostasis in cells. Autophagy is closely related to various physiological or pathological processes. Macromolecular materials are widely used in drug delivery systems and disease treatments due to their intrinsic effects, such as altered pharmacokinetics and biodistribution. Interaction of autophagic flux or the signal pathway with macromolecules may cause autophagy inhibition or autophagy cell death. This review covers autophagy regulation pathways and macromolecular materials (including functional micelles, biodegradable and pH-sensitive polymers, biomacromolecules, dendrimers, coordination polymers, and hybrid nanoparticles) mediated autophagy modulation.

Identifiers

PMID36133340
PMCPMC9470016
OpenAlexW4286356015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.