ArticleFrontiers in endocrinology2022
Specific gut bacterial and fungal microbiota pattern in the first half of pregnancy is linked to the development of gestational
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures.Nutrition & diabetes · 2024Pooled it
- A Review of Gut Microbiota Dynamics: From Healthy Gestation to Gestational Diabetes in Human and Mouse Models.Biomedicines · 2026Review
- Intestinal fungal dysbiosis in gestational diabetes mellitus is associated with adverse pregnancy outcomes.BMC pregnancy and childbirth · 2026Article
- Perinatal phlorizin alleviates maternal high-fat diet-induced metabolic syndrome in female mouse offspring and is associated with modulation of the gut microbiota.Frontiers in nutrition · 2026Article
- The interplay between gut microbiota and gestational diabetes mellitus: mechanisms, characteristics, and intervention strategies.Frontiers in microbiology · 2026Review
- Gut Microbiota and Metabolomics Insights into the Gualou-Xiebai Herb Pair for Dyslipidemia and Atherosclerosis.Journal of microbiology and biotechnology · 2025Article
- A Review of Modulation of Gut Microbiota to Mitigate Gestational Diabetes: Implications for Maternal and Child Health.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- The advantages ofFuture microbiology · 2025Review
- Longitudinal change and causal relationship between gut microbiota and gestational diabetes mellitus.Diabetology & metabolic syndrome · 2025Article
- Overview of Microorganisms: Bacterial Microbiome, Mycobiome, Virome Identified Using Next-Generation Sequencing, and Their Application to Ophthalmic Diseases.Microorganisms · 2025Review
- Unraveling the role of the gut microbiome in pregnancy disorders: insights and implications.Frontiers in cellular and infection microbiology · 2025Review
- Gut mycobiome in cardiometabolic disease progression: current evidence and future directions.Frontiers in microbiology · 2025Review
- Causal Relationship Between Sjögren's Syndrome and Gut Microbiota: A Two-Sample Mendelian Randomization Study.Biomedicines · 2024Article
- Article
- Interactions between host and gut microbiota in gestational diabetes mellitus and their impacts on offspring.BMC microbiology · 2024Review
- Butyrate and iso-butyrate: a new perspective on nutrition prevention of gestational diabetes mellitus.Nutrition & diabetes · 2024Article
- Dynamic changes of gut microbiota between the first and second trimester for women with gestational diabetes mellitus and their correlations with BMI: a nested cohort study in China.Frontiers in microbiology · 2024Article
- Alterations in the Gut Microbiota Composition in Obesity with and without Type 2 Diabetes: A Pilot Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Suppression of certain intestinal microbiota metabolites may lead to gestational diabetes in mice fed a high-fat diet.Frontiers in microbiology · 2024Article
- Gut microbiota interacting with vitamin D but not anandamide might contribute to the pathogenesis of preeclampsia: a preliminary study.Frontiers in cellular and infection microbiology · 2024Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Gestation is linked to changes in gut microbiota composition and function. Since gestational Methods: We collected stool samples from 104 pregnant women including obese individuals (first trimester body mass index median was 26.73). We divided the women into four groups according to routine screening of fasting plasma glucose (FPG) levels and oral glucose tolerance test (oGTT) in the first and third trimesters, respectively. We processed the stool samples for bacterial 16S rRNA and fungal ITS1 genes sequencing by Illumina MiSeq approach and correlated the gut microbiota composition with plasma short-chain fatty acid levels (SCFA). Results: We found that gut bacterial microbiota in the first trimester significantly differs among groups with different GDM onset based on unweighted UniFrac distances (p=0.003). Normoglycemic women had gut microbiota associated with higher abundance of family Prevotellaceae, and order Fusobacteriales, and genus Conclusions: We conclude that there are significant differences in the gut microbiota composition between pregnant women with and without GDM already at the early stage of pregnancy in our cohort that included also overweight and obese individuals. Specific microbial pattern associated with GDM development during early pregnancy and its correlation to plasma lipid or SCFA levels could help to identify women in higher risk of GDM development.
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