Evidence map›Paper›PMID 36133173›Full record

ArticleDiscoveries (Craiova, Romania)

New model predicts in-hospital complications in myocardial infarction.

Geovedy Martinez-Garcia, Miguel Rodriguez-Ramos, Maikel Santos-Medina, Annia Maria Carrero-Vazquez, Yanitsy Chipi-Rodriguez

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Article in Discoveries (Craiova, Romania). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Geovedy Martinez-GarciaCardiology Service, Enrique Cabrera General Teaching Hospital, Havana, Cuba.
Miguel Rodriguez-RamosCardiology Service, Camilo Cienfuegos General Teaching Hospital, Sancti Spiritus, Cuba.
Maikel Santos-MedinaCardiology Service, Dr. Ernesto Guevara de La Serna General Teaching Hospital, Las Tunas, Cuba.
Annia Maria Carrero-VazquezCardiology Service, Enrique Cabrera General Teaching Hospital, Havana, Cuba.
Yanitsy Chipi-RodriguezCardiology Service, Enrique Cabrera General Teaching Hospital, Havana, Cuba.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectivesIschemic cardiopathy constitutes the leading cause of death worldwide. Our aim was to evaluate the prognostic capacity of the leukoglycemic index as well as to create a predictive model of in-hospital complications in patients with ST elevation myocardial infarction. MATERIALS AND

methodsThis was a multicentral and cohort study, which included patients inserted in the Cuban Registry of acute myocardial infarction. The study investigated 900 patients with a validation population represented by 233 external subjects. In order to define the performance of the leukoglycemic index were evaluated the discrimination with the statistical C and the calibration by Hosmer - Lemeshow test. A model of logistic binary regression was employed in order to define the predictive factors. 

resultsOptimal cut point of the leukoglycemic index to predict in-hospital complications was 1188 (sensibility 60%; specificity 61.6%; area under the curve 0.623; p < 0.001). In-hospital complications were significantly higher in the group with the leukoglycemic index ≥ 1188; a higher value was significantly associated with a higher risk to develop an in-hospital complication [RR (IC 95%) = 2.4 (1.804-3.080); p<0.001]. The predictive model proposed is composed by the following factors: age ≥ 66 years, leukoglycemic index ≥ 1188, Killip-Kimball classification ≥ II and medical history of hypertension. This scale had a good discrimination in both, the training and the validation population.

conclusionThe leukoglycemic index possesses a low performance when used to assess the risks for in hospital complications in patients with ST elevation myocardial infarction. The new predictive model has a good performance, which can be applied to estimate risk of in-hospital complications. This model would be able to contribute to the health systems of developing countries without additional cost; it enables prediction of the patients having a higher risk of complications and a negative outcome during the hospitable admission.

Indexed as

in-hospital complicationsleukoglycemic indexprediction.ST elevation myocardial infarction

Identifiers

PMID36133173
PMCPMC9482690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.