Evidence map›Paper›PMID 36133139›Full record

ArticleNanoscale advances2019

Phage-mimicking antibacterial core-shell nanoparticles.

Juliane Hopf, Margo Waters, Veronica Kalwajtys, Katelyn E Carothers, Ryan K Roeder, Joshua D Shrout, Shaun W Lee, Prakash D Nallathamby

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  8. Biocompatible, Multi-Mode, Fluorescent,Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Application of Bacteriophages in Nanotechnology.Nanomaterials (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 3 countries.

Juliane HopfDepartment of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame Notre Dame IN USA.
Margo WatersDepartment of Aerospace and Mechanical Engineering, University of Notre Dame Notre Dame IN USA pnallath@nd.edu +1 574 631 7868.
Veronica KalwajtysDepartment of Biological Sciences, University of Notre Dame Notre Dame IN USA.
Katelyn E CarothersDepartment of Biological Sciences, University of Notre Dame Notre Dame IN USA.
Ryan K RoederDepartment of Aerospace and Mechanical Engineering, University of Notre Dame Notre Dame IN USA pnallath@nd.edu +1 574 631 7868.ORCID https://orcid.org/0000-0003-1576-6570
Joshua D ShroutDepartment of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame Notre Dame IN USA.
Shaun W LeeDepartment of Biological Sciences, University of Notre Dame Notre Dame IN USA.
Prakash D NallathambyDepartment of Aerospace and Mechanical Engineering, University of Notre Dame Notre Dame IN USA pnallath@nd.edu +1 574 631 7868.ORCID https://orcid.org/0000-0001-5064-294X
University of Notre Dame · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing frequency of nosocomial infections caused by antibiotic-resistant microorganisms concurrent with the stagnant discovery of new classes of antibiotics has made the development of new antibacterial agents a critical priority. Our approach is an antibiotic-free strategy drawing inspiration from bacteriophages to combat antibiotic-resistant bacteria. We developed a nanoparticle-based antibacterial system that structurally mimics the protein-turret distribution on the head structure of certain bacteriophages and explored a combination of different materials arranged hierarchically to inhibit bacterial growth and ultimately kill pathogenic bacteria. Here, we describe the synthesis of phage-mimicking antibacterial nanoparticles (ANPs) consisting of silver-coated gold nanospheres distributed randomly on a silica core. The silver-coating was deposited in an anisotropic fashion on the gold nanospheres. Structurally, our nanoparticles mimicked the bacteriophages of the family

Identifiers

PMID36133139
PMCPMC9417579
OpenAlexW2987120930

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.