Evidence map›Paper›PMID 36133047›Full record

ArticleNanoscale advances2020

Eight biomarkers on a novel strip for early diagnosis of acute myocardial infarction.

Li Huang, Yuanchang Zhang, Enben Su, Yuan Liu, Yan Deng, Lian Jin, Zhu Chen, Song Li, Yongxiang Zhao, Nongyue He

Abstract read
In one paragraph

Article in Nanoscale advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li HuangState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University Nanjing 210096 China nyhe1958@163.com.
Yuanchang ZhangGetein Biotechnology Co., Ltd. Nanjing 210000 China.
Enben SuHunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology Zhuzhou 412007 P. R. China.
Yuan LiuState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University Nanjing 210096 China nyhe1958@163.com.
Yan DengGetein Biotechnology Co., Ltd. Nanjing 210000 China.
Lian JinGetein Biotechnology Co., Ltd. Nanjing 210000 China.
Zhu ChenGetein Biotechnology Co., Ltd. Nanjing 210000 China.
Song LiGetein Biotechnology Co., Ltd. Nanjing 210000 China.
Yongxiang ZhaoNational Center for International Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Collaborative Innovation Center for Targeting Tumor Theranostics, Guangxi Medical University Guangxi 530021 China yongxiang_zhao@126.com.
Nongyue HeState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University Nanjing 210096 China nyhe1958@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate detection of markers in human serum is important in the early diagnosis of acute myocardial infarction (AMI). This work presents a novel eight biomarker strip, which combines dry chemistry with a fluorescence lateral flow assay. Eight AMI markers were employed simultaneously for sensitive detection, including cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C), uric acid (UA), myoglobin (Myo), creatine kinase-MB (CK-MB), and cardiac troponin I (cTnI). The strip offers the advantages of simple fabrication, convenience, time-saving detection and accurate assessment for AMI. Moreover, the strip possesses acceptable applicability for human serum. This proposed strategy establishes a remarkable platform for the construction of a multi-target detection strip that is feasible for accurate detection for real human serum samples.

Identifiers

PMID36133047
PMCPMC9419248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.