Evidence map›Paper›PMID 36133012›Full record

ArticleNanoscale advances2021

Aerogels are not regulated as nanomaterials, but can be assessed by tiered testing and grouping strategies for nanomaterials.

Johannes G Keller, Martin Wiemann, Sibylle Gröters, Kai Werle, Antje Vennemann, Robert Landsiedel, Wendel Wohlleben

Abstract read
In one paragraph

Article in Nanoscale advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Data-Driven Review on Aerogels and Polymeric Aerogels.Angewandte Chemie (International ed. in English) · 2025
    Review
  5. Review and Perspectives on the Sustainability of Organic Aerogels.ACS sustainable chemistry & engineering · 2025
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johannes G KellerBASF SE, Dept. Experimental Toxicology and Ecology, Dept. Material Physics 67056 Ludwigshafen Germany wendel.wohlleben@basf.com.
Martin WiemannIBE R&D Institute for Lung Health, gGmbH Münster Germany.
Sibylle GrötersBASF SE, Dept. Experimental Toxicology and Ecology, Dept. Material Physics 67056 Ludwigshafen Germany wendel.wohlleben@basf.com.
Kai WerleBASF SE, Dept. Experimental Toxicology and Ecology, Dept. Material Physics 67056 Ludwigshafen Germany wendel.wohlleben@basf.com.
Antje VennemannIBE R&D Institute for Lung Health, gGmbH Münster Germany.
Robert LandsiedelBASF SE, Dept. Experimental Toxicology and Ecology, Dept. Material Physics 67056 Ludwigshafen Germany wendel.wohlleben@basf.com.
Wendel WohllebenBASF SE, Dept. Experimental Toxicology and Ecology, Dept. Material Physics 67056 Ludwigshafen Germany wendel.wohlleben@basf.com.ORCID https://orcid.org/0000-0003-2094-3260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerogels contribute to an increasing number of novel applications due to many unique properties, such as high porosity and low density. They outperform most other insulation materials, and some are also useful as carriers in food or pharma applications. Aerogels are not nanomaterials by the REACH definition but retain properties of nanoscale structures. Here we applied a testing strategy in three tiers. In Tier 1, we examined a panel of 19 aerogels (functionalized chitosan, alginate, pyrolyzed carbon, silicate, cellulose, polyurethane) for their biosolubility, and oxidative potential. Biosolubility was very limited except for some alginate and silicate aerogels. Oxidative potential, as by the ferric reduction ability of human serum (FRAS), was very low except for one chitosan and pyrolyzed carbon, both of which were <10% of the positive control Mn

Identifiers

PMID36133012
PMCPMC9419173

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.